Genomic Evaluation of Recombination in Small Highly Inbred Beef Cattle Populations

ABSTRACT Meiotic recombination is key for genetic diversity, but its dynamics are underexplored in small inbred beef cattle populations. This study examines recombination in closed beef cattle populations and identifies related genomic regions. Using genotypic data from 1020 Line 1 Hereford and 3420...

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Bibliographic Details
Main Authors: E. Hay, A. S. Ling
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Animal Research and One Health
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Online Access:https://doi.org/10.1002/aro2.103
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Summary:ABSTRACT Meiotic recombination is key for genetic diversity, but its dynamics are underexplored in small inbred beef cattle populations. This study examines recombination in closed beef cattle populations and identifies related genomic regions. Using genotypic data from 1020 Line 1 Hereford and 3420 Composite Gene Combination (CGC) cattle, recombination rates were estimated through offspring and progenitor haplotypes. The CGC composite displayed a higher recombination rate (27.24 events) than the Line 1 population (26.38 events), with reduced rates in Line 1 potentially due to extended homozygous segments. Recombination varied by autosome length, increasing with longer autosomes. A genome‐wide association study revealed novel genomic regions associated with recombination: significantly associated SNP markers were found on Bos taurus autosome (BTA) 1, 7, 13, 15, and 19 in the Line 1 population, and numerous others in the CGC population, indicating complex polygenic influences.
ISSN:2835-5075