Status Epilepticus Due to Severe HHV-6 Encephalitis in an Allogeneic Stem Cell Transplant Recipient
Reactivation of human herpes virus-6 (HHV-6) after stem cell transplantation occurs frequently. It is associated with clinical manifestations varying from nonspecific symptoms such as fevers or rash, to severe life threatening complications including post-transplantation limbic encephalitis. We repo...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2013-12-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
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| Online Access: | http://www.mjhid.org/index.php/mjhid/article/view/1397 |
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| _version_ | 1846096484087365632 |
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| author | Poorvi Chordia Pranatharthi H Chandrasekar |
| author_facet | Poorvi Chordia Pranatharthi H Chandrasekar |
| author_sort | Poorvi Chordia |
| collection | DOAJ |
| description | Reactivation of human herpes virus-6 (HHV-6) after stem cell transplantation occurs frequently. It is associated with clinical manifestations varying from nonspecific symptoms such as fevers or rash, to severe life threatening complications including post-transplantation limbic encephalitis. We report a case of severe HHV-6 encephalitis with viremia in an allogeneic peripheral stem cell transplant recipient who presented with status epilepticus unresponsive to antiepileptic therapy. With intravenous ganciclovir and supportive care, the patient’s condition improved. Awareness of HHV-6 infection in stem cell transplant recipients may help with early diagnosis and improved outcome. |
| format | Article |
| id | doaj-art-73033ebc31be4ed1872a0962b3001c8e |
| institution | Kabale University |
| issn | 2035-3006 |
| language | English |
| publishDate | 2013-12-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-73033ebc31be4ed1872a0962b3001c8e2025-01-02T06:46:07ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062013-12-0161e2014008e201400810.4084/mjhid.2014.0081157Status Epilepticus Due to Severe HHV-6 Encephalitis in an Allogeneic Stem Cell Transplant RecipientPoorvi Chordia0Pranatharthi H Chandrasekar1Wayne State UniversityWayne State University, School of MedicineReactivation of human herpes virus-6 (HHV-6) after stem cell transplantation occurs frequently. It is associated with clinical manifestations varying from nonspecific symptoms such as fevers or rash, to severe life threatening complications including post-transplantation limbic encephalitis. We report a case of severe HHV-6 encephalitis with viremia in an allogeneic peripheral stem cell transplant recipient who presented with status epilepticus unresponsive to antiepileptic therapy. With intravenous ganciclovir and supportive care, the patient’s condition improved. Awareness of HHV-6 infection in stem cell transplant recipients may help with early diagnosis and improved outcome.http://www.mjhid.org/index.php/mjhid/article/view/1397HHV-6encephalitis, stem cell transplant |
| spellingShingle | Poorvi Chordia Pranatharthi H Chandrasekar Status Epilepticus Due to Severe HHV-6 Encephalitis in an Allogeneic Stem Cell Transplant Recipient Mediterranean Journal of Hematology and Infectious Diseases HHV-6 encephalitis, stem cell transplant |
| title | Status Epilepticus Due to Severe HHV-6 Encephalitis in an Allogeneic Stem Cell Transplant Recipient |
| title_full | Status Epilepticus Due to Severe HHV-6 Encephalitis in an Allogeneic Stem Cell Transplant Recipient |
| title_fullStr | Status Epilepticus Due to Severe HHV-6 Encephalitis in an Allogeneic Stem Cell Transplant Recipient |
| title_full_unstemmed | Status Epilepticus Due to Severe HHV-6 Encephalitis in an Allogeneic Stem Cell Transplant Recipient |
| title_short | Status Epilepticus Due to Severe HHV-6 Encephalitis in an Allogeneic Stem Cell Transplant Recipient |
| title_sort | status epilepticus due to severe hhv 6 encephalitis in an allogeneic stem cell transplant recipient |
| topic | HHV-6 encephalitis, stem cell transplant |
| url | http://www.mjhid.org/index.php/mjhid/article/view/1397 |
| work_keys_str_mv | AT poorvichordia statusepilepticusduetoseverehhv6encephalitisinanallogeneicstemcelltransplantrecipient AT pranatharthihchandrasekar statusepilepticusduetoseverehhv6encephalitisinanallogeneicstemcelltransplantrecipient |