Effects supplementation of novel multi-enzyme on laying performance, egg quality, and intestinal health and digestive function of laying hens

This study investigated the effects of multi-enzyme supplementation on various aspects of laying hens, including laying performance, egg quality, intestinal health and digestive function. In total, 384 Jingfen No.6 laying hens at 65-week-age were randomly assigned to four distinct dietary treatments...

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Main Authors: Qixin Huang, Wuzhou Yi, Jinghui Fan, Rui Chen, Xin Ma, Zhou Chen, Wenzi Wu, Lichun Qian
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Poultry Science
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Online Access:http://www.sciencedirect.com/science/article/pii/S0032579124010393
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author Qixin Huang
Wuzhou Yi
Jinghui Fan
Rui Chen
Xin Ma
Zhou Chen
Wenzi Wu
Lichun Qian
author_facet Qixin Huang
Wuzhou Yi
Jinghui Fan
Rui Chen
Xin Ma
Zhou Chen
Wenzi Wu
Lichun Qian
author_sort Qixin Huang
collection DOAJ
description This study investigated the effects of multi-enzyme supplementation on various aspects of laying hens, including laying performance, egg quality, intestinal health and digestive function. In total, 384 Jingfen No.6 laying hens at 65-week-age were randomly assigned to four distinct dietary treatments: a basal diet (CON), CON supplemented with 150 g/t multi-enzyme (T1), CON with 300 g/t multi-enzyme (T2), and 600 g/t multi-enzyme (T3). A significant linear (P = 0.044) and quadratic (P = 0.014) increase was observed in the laying rate, while the feed/egg ratio exhibited a linear (P = 0.001) and quadratic (P < 0.001) decrease with increasing multi-enzyme supplementation. Additionally, linear (P < 0.05) and quadratic (P < 0.05) increases were observed in yolk rate and haugh unit with increasing levels of multi-enzyme supplementation. The trypsin activity in the duodenum and crude protein digestibility showed linear (P < 0.05) and quadratic (P < 0.05) increase with the addition of multi-enzyme. Furthermore, lipase and amylase activities in the duodenum increased quadratically (P = 0.041) and linearly (P = 0.040), respectively. Both jejunal and ileal digesta viscosities showed linear (P < 0.05) and quadratic (P < 0.05) decrease with the increasing addition of multi-enzyme. Moreover, multi-enzyme supplementation significantly increased (P < 0.05) the number of goblet cells in the intestinal of the treatment groups. The mRNA expression of Occludin-1, mucin 2 (MUC-2), large neutral amino acids transporter small subunit 1 (LAT-1) in the jejunum were significantly increased (P < 0.05) in the treatment groups (T1, T2 and T3) compared to the CON group. Additionally, the mRNA expression of solute carrier family 6-member 19 (B0AT-1) and large neutral amino acids transporter small subunit 4 (LAT-4) were significantly evaluated (P < 0.05) in the T2 and T3 groups, respectively. In conclusion, multi-enzyme supplementation enhanced digestive enzyme activities and intestinal barrier function, reduced intestinal digesta viscosity, and regulated mRNA expression of intestinal amino acid and lipid transporter genes, thereby improving crude protein digestibility and positively affecting laying performance and egg quality in hens.
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series Poultry Science
spelling doaj-art-72c34746f8c842f1a6b065dca82b03be2024-12-14T06:29:19ZengElsevierPoultry Science0032-57912024-12-0110312104461Effects supplementation of novel multi-enzyme on laying performance, egg quality, and intestinal health and digestive function of laying hensQixin Huang0Wuzhou Yi1Jinghui Fan2Rui Chen3Xin Ma4Zhou Chen5Wenzi Wu6Lichun Qian7Key Laboratory of Animal Nutrition and Feed Science in East China, Ministry of Agriculture, College of Animal Sciences, Zhejiang University, Hangzhou 310058, PR ChinaKey Laboratory of Animal Nutrition and Feed Science in East China, Ministry of Agriculture, College of Animal Sciences, Zhejiang University, Hangzhou 310058, PR ChinaHainan Institute of Zhejiang University, Sanya 572025, PR ChinaKey Laboratory of Animal Nutrition and Feed Science in East China, Ministry of Agriculture, College of Animal Sciences, Zhejiang University, Hangzhou 310058, PR China; Hainan Institute of Zhejiang University, Sanya 572025, PR ChinaKey Laboratory of Animal Nutrition and Feed Science in East China, Ministry of Agriculture, College of Animal Sciences, Zhejiang University, Hangzhou 310058, PR ChinaKey Laboratory of Animal Nutrition and Feed Science in East China, Ministry of Agriculture, College of Animal Sciences, Zhejiang University, Hangzhou 310058, PR China; Hangzhou Academy of Agricultural Sciences, Hangzhou 310004, PR ChinaKey Laboratory of Animal Nutrition and Feed Science in East China, Ministry of Agriculture, College of Animal Sciences, Zhejiang University, Hangzhou 310058, PR China; Hangzhou Academy of Agricultural Sciences, Hangzhou 310004, PR ChinaKey Laboratory of Animal Nutrition and Feed Science in East China, Ministry of Agriculture, College of Animal Sciences, Zhejiang University, Hangzhou 310058, PR China; Corresponding author.This study investigated the effects of multi-enzyme supplementation on various aspects of laying hens, including laying performance, egg quality, intestinal health and digestive function. In total, 384 Jingfen No.6 laying hens at 65-week-age were randomly assigned to four distinct dietary treatments: a basal diet (CON), CON supplemented with 150 g/t multi-enzyme (T1), CON with 300 g/t multi-enzyme (T2), and 600 g/t multi-enzyme (T3). A significant linear (P = 0.044) and quadratic (P = 0.014) increase was observed in the laying rate, while the feed/egg ratio exhibited a linear (P = 0.001) and quadratic (P < 0.001) decrease with increasing multi-enzyme supplementation. Additionally, linear (P < 0.05) and quadratic (P < 0.05) increases were observed in yolk rate and haugh unit with increasing levels of multi-enzyme supplementation. The trypsin activity in the duodenum and crude protein digestibility showed linear (P < 0.05) and quadratic (P < 0.05) increase with the addition of multi-enzyme. Furthermore, lipase and amylase activities in the duodenum increased quadratically (P = 0.041) and linearly (P = 0.040), respectively. Both jejunal and ileal digesta viscosities showed linear (P < 0.05) and quadratic (P < 0.05) decrease with the increasing addition of multi-enzyme. Moreover, multi-enzyme supplementation significantly increased (P < 0.05) the number of goblet cells in the intestinal of the treatment groups. The mRNA expression of Occludin-1, mucin 2 (MUC-2), large neutral amino acids transporter small subunit 1 (LAT-1) in the jejunum were significantly increased (P < 0.05) in the treatment groups (T1, T2 and T3) compared to the CON group. Additionally, the mRNA expression of solute carrier family 6-member 19 (B0AT-1) and large neutral amino acids transporter small subunit 4 (LAT-4) were significantly evaluated (P < 0.05) in the T2 and T3 groups, respectively. In conclusion, multi-enzyme supplementation enhanced digestive enzyme activities and intestinal barrier function, reduced intestinal digesta viscosity, and regulated mRNA expression of intestinal amino acid and lipid transporter genes, thereby improving crude protein digestibility and positively affecting laying performance and egg quality in hens.http://www.sciencedirect.com/science/article/pii/S0032579124010393EnzymePerformanceEgg qualityIntestinal healthLaying hen
spellingShingle Qixin Huang
Wuzhou Yi
Jinghui Fan
Rui Chen
Xin Ma
Zhou Chen
Wenzi Wu
Lichun Qian
Effects supplementation of novel multi-enzyme on laying performance, egg quality, and intestinal health and digestive function of laying hens
Poultry Science
Enzyme
Performance
Egg quality
Intestinal health
Laying hen
title Effects supplementation of novel multi-enzyme on laying performance, egg quality, and intestinal health and digestive function of laying hens
title_full Effects supplementation of novel multi-enzyme on laying performance, egg quality, and intestinal health and digestive function of laying hens
title_fullStr Effects supplementation of novel multi-enzyme on laying performance, egg quality, and intestinal health and digestive function of laying hens
title_full_unstemmed Effects supplementation of novel multi-enzyme on laying performance, egg quality, and intestinal health and digestive function of laying hens
title_short Effects supplementation of novel multi-enzyme on laying performance, egg quality, and intestinal health and digestive function of laying hens
title_sort effects supplementation of novel multi enzyme on laying performance egg quality and intestinal health and digestive function of laying hens
topic Enzyme
Performance
Egg quality
Intestinal health
Laying hen
url http://www.sciencedirect.com/science/article/pii/S0032579124010393
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