Vacuolar ATPase as a potential therapeutic target and mediator of treatment resistance in cancer
Abstract Vacuolar ATPase (V‐ATPase) is an ATP‐dependent H+‐transporter that pumps protons across intracellular and plasma membranes. It consists of a large multi‐subunit protein complex and influences a wide range of cellular processes. This review focuses on emerging evidence for the roles for V‐AT...
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| Main Authors: | Bradleigh Whitton, Haruko Okamoto, Graham Packham, Simon J. Crabb |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-08-01
|
| Series: | Cancer Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/cam4.1594 |
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