Pediatric Ovarian Yolk Sac Tumor Mimicking Appendicitis: A Case Report From a Low‐Resource Setting
ABSTRACT Ovarian yolk sac tumors (OYSTs), also known as endodermal sinus tumors, are rare and highly malignant germ cell tumors, accounting for approximately 1% of all ovarian cancers. They predominantly affect children and young adults, with a rapid growth rate and early metastasis, making early di...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-12-01
|
| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.70013 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846108005470306304 |
|---|---|
| author | William Nkenguye Alex Mremi Peter Minja Jay Lodhia |
| author_facet | William Nkenguye Alex Mremi Peter Minja Jay Lodhia |
| author_sort | William Nkenguye |
| collection | DOAJ |
| description | ABSTRACT Ovarian yolk sac tumors (OYSTs), also known as endodermal sinus tumors, are rare and highly malignant germ cell tumors, accounting for approximately 1% of all ovarian cancers. They predominantly affect children and young adults, with a rapid growth rate and early metastasis, making early diagnosis and treatment crucial. This report presents the case of a 6‐year‐old female from a low‐resource setting who initially presented with symptoms suggestive of acute appendicitis, including abdominal pain, fever, and vomiting. This was supported by a CT scan; however, intraoperative findings revealed a large right ovarian mass, which was surgically excised via cystectomy and histologically confirmed as an OYST. The patient recovered well postoperatively and was referred for oncological management. This case underscores the importance of considering OYSTs in the differential diagnosis of pediatric abdominal masses and highlights the necessity of a multidisciplinary approach for optimal patient outcomes. Enhanced awareness and improved diagnostic strategies are essential for better management of this rare tumor, particularly in resource‐limited settings. |
| format | Article |
| id | doaj-art-727c7ebfbd4d4221b83ec44ad7cf3db4 |
| institution | Kabale University |
| issn | 2050-0904 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj-art-727c7ebfbd4d4221b83ec44ad7cf3db42024-12-26T06:30:43ZengWileyClinical Case Reports2050-09042024-12-011212n/an/a10.1002/ccr3.70013Pediatric Ovarian Yolk Sac Tumor Mimicking Appendicitis: A Case Report From a Low‐Resource SettingWilliam Nkenguye0Alex Mremi1Peter Minja2Jay Lodhia3Department of Epidemiology and Applied Biostatistics Kilimanjaro Christian Medical University College Moshi TanzaniaKilimanjaro Clinical Research Institute Kilimanjaro Christian Medical Centre Moshi TanzaniaDepartment of General Surgery Kilimanjaro Christian Medical Centre Moshi TanzaniaFaculty of Medicine Kilimanjaro Christian Medical University College Moshi TanzaniaABSTRACT Ovarian yolk sac tumors (OYSTs), also known as endodermal sinus tumors, are rare and highly malignant germ cell tumors, accounting for approximately 1% of all ovarian cancers. They predominantly affect children and young adults, with a rapid growth rate and early metastasis, making early diagnosis and treatment crucial. This report presents the case of a 6‐year‐old female from a low‐resource setting who initially presented with symptoms suggestive of acute appendicitis, including abdominal pain, fever, and vomiting. This was supported by a CT scan; however, intraoperative findings revealed a large right ovarian mass, which was surgically excised via cystectomy and histologically confirmed as an OYST. The patient recovered well postoperatively and was referred for oncological management. This case underscores the importance of considering OYSTs in the differential diagnosis of pediatric abdominal masses and highlights the necessity of a multidisciplinary approach for optimal patient outcomes. Enhanced awareness and improved diagnostic strategies are essential for better management of this rare tumor, particularly in resource‐limited settings.https://doi.org/10.1002/ccr3.70013alpha‐fetoproteinappendicitisgerm cell tumorovarian yolk sac tumorpediatric malignancy |
| spellingShingle | William Nkenguye Alex Mremi Peter Minja Jay Lodhia Pediatric Ovarian Yolk Sac Tumor Mimicking Appendicitis: A Case Report From a Low‐Resource Setting Clinical Case Reports alpha‐fetoprotein appendicitis germ cell tumor ovarian yolk sac tumor pediatric malignancy |
| title | Pediatric Ovarian Yolk Sac Tumor Mimicking Appendicitis: A Case Report From a Low‐Resource Setting |
| title_full | Pediatric Ovarian Yolk Sac Tumor Mimicking Appendicitis: A Case Report From a Low‐Resource Setting |
| title_fullStr | Pediatric Ovarian Yolk Sac Tumor Mimicking Appendicitis: A Case Report From a Low‐Resource Setting |
| title_full_unstemmed | Pediatric Ovarian Yolk Sac Tumor Mimicking Appendicitis: A Case Report From a Low‐Resource Setting |
| title_short | Pediatric Ovarian Yolk Sac Tumor Mimicking Appendicitis: A Case Report From a Low‐Resource Setting |
| title_sort | pediatric ovarian yolk sac tumor mimicking appendicitis a case report from a low resource setting |
| topic | alpha‐fetoprotein appendicitis germ cell tumor ovarian yolk sac tumor pediatric malignancy |
| url | https://doi.org/10.1002/ccr3.70013 |
| work_keys_str_mv | AT williamnkenguye pediatricovarianyolksactumormimickingappendicitisacasereportfromalowresourcesetting AT alexmremi pediatricovarianyolksactumormimickingappendicitisacasereportfromalowresourcesetting AT peterminja pediatricovarianyolksactumormimickingappendicitisacasereportfromalowresourcesetting AT jaylodhia pediatricovarianyolksactumormimickingappendicitisacasereportfromalowresourcesetting |