Mandibular metastasis of cutaneous melanoma
Melanoma is a malignant neoplasm of melanocytes that can metastasize to every organ of the body, but metastasis to the oral cavity is uncommon. We describe a case of metastatic malignant melanoma to the mandible in a 33-years-old woman. The patient had a 2 cm × 4 cm firm, ulcerated nodule, distal to...
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| Format: | Article |
| Language: | English |
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Elsevier
2016-09-01
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| Series: | Journal of Oral Biology and Craniofacial Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2212426816300240 |
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| author | Josi Amadeu Cleto Mariosvaldo Piazzetta Cassius Carvalho Torres-Pereira José Miguel Amenábar |
| author_facet | Josi Amadeu Cleto Mariosvaldo Piazzetta Cassius Carvalho Torres-Pereira José Miguel Amenábar |
| author_sort | Josi Amadeu |
| collection | DOAJ |
| description | Melanoma is a malignant neoplasm of melanocytes that can metastasize to every organ of the body, but metastasis to the oral cavity is uncommon. We describe a case of metastatic malignant melanoma to the mandible in a 33-years-old woman. The patient had a 2 cm × 4 cm firm, ulcerated nodule, distal to the second mandibular right molar. Incisional biopsy revealed epithelioid cells and immunohistochemistry was positive for HMB-45, S-100 protein and vimentin. The patient was referred to the local cancer hospital for treatment but died 3 months later. Metastatic malignant melanomas of the oral cavity are rare and unusual. Early diagnosis of the primary tumor is essential for successful treatment and to improvement of patient prognosis. |
| format | Article |
| id | doaj-art-7261e5c089ee43e483955baa2a0a86a5 |
| institution | Kabale University |
| issn | 2212-4268 |
| language | English |
| publishDate | 2016-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Oral Biology and Craniofacial Research |
| spelling | doaj-art-7261e5c089ee43e483955baa2a0a86a52024-11-23T06:27:04ZengElsevierJournal of Oral Biology and Craniofacial Research2212-42682016-09-0163250252Mandibular metastasis of cutaneous melanomaJosi Amadeu0Cleto Mariosvaldo Piazzetta1Cassius Carvalho Torres-Pereira2José Miguel Amenábar3Corresponding author at: Stomatology Department, Universidade Federal do Paraná, Av. Lothário Meissner 632, Jardim Botânico, Curitiba, Paraná CEP 80210-170, Brazil. Tel.: +55 41 3360 4024; fax: +55 41 3360 4053.; Stomatology Department, Universidade Federal do Paraná, Curitiba, PR, BrazilStomatology Department, Universidade Federal do Paraná, Curitiba, PR, BrazilStomatology Department, Universidade Federal do Paraná, Curitiba, PR, BrazilStomatology Department, Universidade Federal do Paraná, Curitiba, PR, BrazilMelanoma is a malignant neoplasm of melanocytes that can metastasize to every organ of the body, but metastasis to the oral cavity is uncommon. We describe a case of metastatic malignant melanoma to the mandible in a 33-years-old woman. The patient had a 2 cm × 4 cm firm, ulcerated nodule, distal to the second mandibular right molar. Incisional biopsy revealed epithelioid cells and immunohistochemistry was positive for HMB-45, S-100 protein and vimentin. The patient was referred to the local cancer hospital for treatment but died 3 months later. Metastatic malignant melanomas of the oral cavity are rare and unusual. Early diagnosis of the primary tumor is essential for successful treatment and to improvement of patient prognosis.http://www.sciencedirect.com/science/article/pii/S2212426816300240MelanomaMandibleNeoplasm metastasis |
| spellingShingle | Josi Amadeu Cleto Mariosvaldo Piazzetta Cassius Carvalho Torres-Pereira José Miguel Amenábar Mandibular metastasis of cutaneous melanoma Journal of Oral Biology and Craniofacial Research Melanoma Mandible Neoplasm metastasis |
| title | Mandibular metastasis of cutaneous melanoma |
| title_full | Mandibular metastasis of cutaneous melanoma |
| title_fullStr | Mandibular metastasis of cutaneous melanoma |
| title_full_unstemmed | Mandibular metastasis of cutaneous melanoma |
| title_short | Mandibular metastasis of cutaneous melanoma |
| title_sort | mandibular metastasis of cutaneous melanoma |
| topic | Melanoma Mandible Neoplasm metastasis |
| url | http://www.sciencedirect.com/science/article/pii/S2212426816300240 |
| work_keys_str_mv | AT josiamadeu mandibularmetastasisofcutaneousmelanoma AT cletomariosvaldopiazzetta mandibularmetastasisofcutaneousmelanoma AT cassiuscarvalhotorrespereira mandibularmetastasisofcutaneousmelanoma AT josemiguelamenabar mandibularmetastasisofcutaneousmelanoma |