定量 PCR 分析 HBsAg 阳性肝癌患者 手术前后血清 HBV DNA 变化
目的: 明确外科手术对 HBsAg 阳性肝癌患者乙型肝炎病毒(HBV)复制的影响。 方法: 以常规聚合酶链反应 ( PCR)方法检测了 20 例 HBV 血清学标志阳性肝癌患者血清中的 HBV DNA ; 应用荧光能量转移定量聚合酶链反应(QPCR) 测定肝癌手术切除前后病人血清中 HBV DNA 量的变化情况。结果: 在部分肝癌病人( 40%)血清中可以检测到 HBV DNA ; 外科手术后较手术前病人血清 HBV DNA 拷贝数增高(P <0. 01)。结论: 乙型肝炎病毒仍然在大部分肝癌病人体内进行着 活跃的复制; 外科干预在部分病人中引起病毒复制增加。...
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Format: | Article |
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Language: | zho |
Published: |
Editorial Office of Journal of Sun Yat-sen University
1998-01-01
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Series: | Zhongshan Daxue xuebao. Yixue kexue ban |
Online Access: | http://xuebaoyx.sysu.edu.cn/zh/article/43588924/ |
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