The Potential of Swiftlet Bird's Nest Extract (Aerodramus fucipaghus) as an Antioxidant and Serum Formulation
The white swiftlet bird's nest (Aerodramus fucipaghus) constitutes one of nature's treasures endowed with diverse health benefits. The swiftlet bird's nest is a potential source of antioxidants, capable of counteracting free radicals contributing to premature ageing. It can be harness...
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| Format: | Article |
| Language: | English |
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Universitas Ahmad Dahlan
2024-11-01
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| Series: | Pharmaciana |
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| Online Access: | https://journal.uad.ac.id/index.php/PHARMACIANA/article/view/27001 |
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| author | Naniek Widyaningrum Chintiana Nindya Putri Thendi Abdul Arief Nada Aini Sofa Monica Virdaus |
| author_facet | Naniek Widyaningrum Chintiana Nindya Putri Thendi Abdul Arief Nada Aini Sofa Monica Virdaus |
| author_sort | Naniek Widyaningrum |
| collection | DOAJ |
| description | The white swiftlet bird's nest (Aerodramus fucipaghus) constitutes one of nature's treasures endowed with diverse health benefits. The swiftlet bird's nest is a potential source of antioxidants, capable of counteracting free radicals contributing to premature ageing. It can be harnessed as a serum formulation featuring small molecules, facilitating deeper skin penetration, efficient delivery of highly concentrated active agents, and expedited resolution of skin issues. This study aimed to ascertain the swiftlet bird's nest serum's physical properties, physical stability, and antioxidant activities. Serum formulations span a range of concentrations: 10%, 20%, 30%, and 40%. Physical attributes of the serum, including organoleptic properties, homogeneity, pH, spreadability, and viscosity, were observed. Serum stability was assessed over a 21-day storage period. The antioxidant activity of the serum was gauged via DPPH assay, determining the IC50 values. The serum, across varying concentrations, exhibited commendable physical characteristics, satisfying stipulated criteria. Antioxidant activity was detected in the serum across a spectrum of concentrations, revealing IC50 values of 250.00 µg/mL, signifying a range from weak to strong efficacy (90.137 µg/mL). The swiftlet bird's nest serum with its concentration variants demonstrated physical stability during the 21-day storage duration. Drawing from the research, it can be deduced that the swiftlet bird's nest holds promise for development into a serum formulation that fulfils both physical and stability criteria, endowed with robust antioxidant activity. Notably, the swiftlet bird's nest serum at a 40% concentration exhibited potent antioxidant activity, manifesting an IC50 value of 90.137 µg/mL |
| format | Article |
| id | doaj-art-723a0b20bbe3445b81770c93b8a62f86 |
| institution | Kabale University |
| issn | 2088-4559 2477-0256 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Universitas Ahmad Dahlan |
| record_format | Article |
| series | Pharmaciana |
| spelling | doaj-art-723a0b20bbe3445b81770c93b8a62f862025-01-12T00:37:14ZengUniversitas Ahmad DahlanPharmaciana2088-45592477-02562024-11-0114310.12928/pharmaciana.v14i3.2700119590The Potential of Swiftlet Bird's Nest Extract (Aerodramus fucipaghus) as an Antioxidant and Serum FormulationNaniek Widyaningrum0Chintiana Nindya Putri1Thendi Abdul Arief2Nada Aini Sofa3Monica Virdaus4Professional Pharmacy Education Program, Universitas Islam Sultan AgungProfessional Pharmacy Education Program, Universitas Islam Sultan AgungProfessional Pharmacy Education Program, Universitas Islam Sultan AgungUniversitas Islam Sultan AgungPharmaceutical Science Study Program, Universitas Islam Sultan AgungThe white swiftlet bird's nest (Aerodramus fucipaghus) constitutes one of nature's treasures endowed with diverse health benefits. The swiftlet bird's nest is a potential source of antioxidants, capable of counteracting free radicals contributing to premature ageing. It can be harnessed as a serum formulation featuring small molecules, facilitating deeper skin penetration, efficient delivery of highly concentrated active agents, and expedited resolution of skin issues. This study aimed to ascertain the swiftlet bird's nest serum's physical properties, physical stability, and antioxidant activities. Serum formulations span a range of concentrations: 10%, 20%, 30%, and 40%. Physical attributes of the serum, including organoleptic properties, homogeneity, pH, spreadability, and viscosity, were observed. Serum stability was assessed over a 21-day storage period. The antioxidant activity of the serum was gauged via DPPH assay, determining the IC50 values. The serum, across varying concentrations, exhibited commendable physical characteristics, satisfying stipulated criteria. Antioxidant activity was detected in the serum across a spectrum of concentrations, revealing IC50 values of 250.00 µg/mL, signifying a range from weak to strong efficacy (90.137 µg/mL). The swiftlet bird's nest serum with its concentration variants demonstrated physical stability during the 21-day storage duration. Drawing from the research, it can be deduced that the swiftlet bird's nest holds promise for development into a serum formulation that fulfils both physical and stability criteria, endowed with robust antioxidant activity. Notably, the swiftlet bird's nest serum at a 40% concentration exhibited potent antioxidant activity, manifesting an IC50 value of 90.137 µg/mLhttps://journal.uad.ac.id/index.php/PHARMACIANA/article/view/27001Swiftlet Bird's NestAerodramus fucipaghusSerumAntioxidantDPPH |
| spellingShingle | Naniek Widyaningrum Chintiana Nindya Putri Thendi Abdul Arief Nada Aini Sofa Monica Virdaus The Potential of Swiftlet Bird's Nest Extract (Aerodramus fucipaghus) as an Antioxidant and Serum Formulation Pharmaciana Swiftlet Bird's Nest Aerodramus fucipaghus Serum Antioxidant DPPH |
| title | The Potential of Swiftlet Bird's Nest Extract (Aerodramus fucipaghus) as an Antioxidant and Serum Formulation |
| title_full | The Potential of Swiftlet Bird's Nest Extract (Aerodramus fucipaghus) as an Antioxidant and Serum Formulation |
| title_fullStr | The Potential of Swiftlet Bird's Nest Extract (Aerodramus fucipaghus) as an Antioxidant and Serum Formulation |
| title_full_unstemmed | The Potential of Swiftlet Bird's Nest Extract (Aerodramus fucipaghus) as an Antioxidant and Serum Formulation |
| title_short | The Potential of Swiftlet Bird's Nest Extract (Aerodramus fucipaghus) as an Antioxidant and Serum Formulation |
| title_sort | potential of swiftlet bird s nest extract aerodramus fucipaghus as an antioxidant and serum formulation |
| topic | Swiftlet Bird's Nest Aerodramus fucipaghus Serum Antioxidant DPPH |
| url | https://journal.uad.ac.id/index.php/PHARMACIANA/article/view/27001 |
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