Hypoxia signature derived from tumor-associated endothelial cells predict prognosis in gastric cancer

Hypoxia signature derived from tumor-associated endothelial cells predict prognosis in gastric cancer

BackgroundA hypoxic metabolism environment in the tumors is often associated with poor prognostic events such as tumor progression and treatment resistance. In gastric cancer, the mechanism of how hypoxia metabolism affects the tumor microenvironment and immunotherapy efficacy remains to be elucidat...

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Bibliographic Details
Main Authors: Ruiheng Wang, Guijun Liu, Ke Wang, Zhanglei Pan, Zhihua Pei, Xijiao Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
gastric cancer
immunotherapy
single-cell
endothelial cells
hypoxia
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1515681/full
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