Long-term Outcomes of Patients with Giant Hydronephrosis After Pyeloplasty

Objective: The study aims to assess the long-term outcomes of pyeloplasty performed for ureteropelvic junction obstruction (UPJO) with giant hydronephrosis (GH). Method: Data of 94 patients with ipsilateral UPJO patients who underwent pyeloplasty were analyzed. Patients’ demographic characteristics...

Full description

Saved in:
Bibliographic Details
Main Authors: Ayşe Başak Uçan, Begüm Sönmez, Ayşe Demet Payza, Arzu Şencan
Format: Article
Language:English
Published: Galenos Publishing House 2024-12-01
Series:Journal of Behçet Uz Children's Hospital
Subjects:
Online Access:https://jag.journalagent.com/z4/download_fulltext.asp?pdir=behcetuz&plng=eng&un=BUCHD-79989
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1846126869012807680
author Ayşe Başak Uçan
Begüm Sönmez
Ayşe Demet Payza
Arzu Şencan
author_facet Ayşe Başak Uçan
Begüm Sönmez
Ayşe Demet Payza
Arzu Şencan
author_sort Ayşe Başak Uçan
collection DOAJ
description Objective: The study aims to assess the long-term outcomes of pyeloplasty performed for ureteropelvic junction obstruction (UPJO) with giant hydronephrosis (GH). Method: Data of 94 patients with ipsilateral UPJO patients who underwent pyeloplasty were analyzed. Patients’ demographic characteristics, pre-, and postoperative anteroposterior diameters (APDs) of their kidneys, parenchymal thickness (PT) ratio (PT of ipsilateral/contralateral kidneys) of kidneys, differential renal function (DRF) and surgical outcomes were compared between the GH (group of patients with AP diameter of at least 50 mm as measured on two ultrasonographys with thinner PT than ½ of the contralateral kidney) and the non-GH groups. Results: Six female, and 18 male children were included in the GH (mean APD: 60.46±9.25 mm), and the remaining 21 female, and 49 male patients in the non-GH group were used as controls. Preoperative PT ratios and DRFs were found to be impaired in the GH group compared to the non-GH group (p<0,05). No significant differences were found between the groups in terms of age, gender, laterality of pyeloplasty, operative success. APD and PT ratios of GH and non-GH groups of patients. APD and PT ratios were found to improve significantly after pyeloplasty (p<0.05). GH patients who underwent pyeloplasty before 1 year of age experienced significant improvement in their DRFs and PT ratios, while these parameters did not improve in older children who underwent pyeloplasty. Conclusion: Long-term outcomes of pyeloplasty are satisfactory in pediatric UPJO patients with GH, and their DRFs were stable even in late renograms. Early relief of the obstruction improves PT and renal functions in GH patients younger than 1 year of age.
format Article
id doaj-art-7217658f5af5449983226bcf4de43690
institution Kabale University
issn 2822-4469
language English
publishDate 2024-12-01
publisher Galenos Publishing House
record_format Article
series Journal of Behçet Uz Children's Hospital
spelling doaj-art-7217658f5af5449983226bcf4de436902024-12-12T08:41:50ZengGalenos Publishing HouseJournal of Behçet Uz Children's Hospital2822-44692024-12-0114314615210.4274/jbuch.galenos.2024.79989Long-term Outcomes of Patients with Giant Hydronephrosis After PyeloplastyAyşe Başak Uçan0https://orcid.org/0000-0002-1521-6053Begüm Sönmez1https://orcid.org/0009-0004-1085-7769Ayşe Demet Payza2https://orcid.org/0009-0002-9121-775XArzu Şencan3https://orcid.org/0000-0003-4499-7984University of Health Sciences Turkey, Dr. Behçet Uz Pediatric Diseases and Surgery Training and Research Hospital, Clinic of Pediatric Surgery, İzmir, TurkeyUniversity of Health Sciences Turkey, Dr. Behçet Uz Pediatric Diseases and Surgery Training and Research Hospital, Clinic of Pediatric Surgery, İzmir, TurkeyUniversity of Health Sciences Turkey, Dr. Behçet Uz Pediatric Diseases and Surgery Training and Research Hospital, Clinic of Pediatric Surgery, İzmir, TurkeyUniversity of Health Sciences Turkey, Dr. Behçet Uz Pediatric Diseases and Surgery Training and Research Hospital, Clinic of Pediatric Surgery, İzmir, TurkeyObjective: The study aims to assess the long-term outcomes of pyeloplasty performed for ureteropelvic junction obstruction (UPJO) with giant hydronephrosis (GH). Method: Data of 94 patients with ipsilateral UPJO patients who underwent pyeloplasty were analyzed. Patients’ demographic characteristics, pre-, and postoperative anteroposterior diameters (APDs) of their kidneys, parenchymal thickness (PT) ratio (PT of ipsilateral/contralateral kidneys) of kidneys, differential renal function (DRF) and surgical outcomes were compared between the GH (group of patients with AP diameter of at least 50 mm as measured on two ultrasonographys with thinner PT than ½ of the contralateral kidney) and the non-GH groups. Results: Six female, and 18 male children were included in the GH (mean APD: 60.46±9.25 mm), and the remaining 21 female, and 49 male patients in the non-GH group were used as controls. Preoperative PT ratios and DRFs were found to be impaired in the GH group compared to the non-GH group (p<0,05). No significant differences were found between the groups in terms of age, gender, laterality of pyeloplasty, operative success. APD and PT ratios of GH and non-GH groups of patients. APD and PT ratios were found to improve significantly after pyeloplasty (p<0.05). GH patients who underwent pyeloplasty before 1 year of age experienced significant improvement in their DRFs and PT ratios, while these parameters did not improve in older children who underwent pyeloplasty. Conclusion: Long-term outcomes of pyeloplasty are satisfactory in pediatric UPJO patients with GH, and their DRFs were stable even in late renograms. Early relief of the obstruction improves PT and renal functions in GH patients younger than 1 year of age.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=behcetuz&plng=eng&un=BUCHD-79989differential renal functionpoorly functioning kidneypyeloplastyureteropelvic junction obstructionrenal parenchymal thickness
spellingShingle Ayşe Başak Uçan
Begüm Sönmez
Ayşe Demet Payza
Arzu Şencan
Long-term Outcomes of Patients with Giant Hydronephrosis After Pyeloplasty
Journal of Behçet Uz Children's Hospital
differential renal function
poorly functioning kidney
pyeloplasty
ureteropelvic junction obstruction
renal parenchymal thickness
title Long-term Outcomes of Patients with Giant Hydronephrosis After Pyeloplasty
title_full Long-term Outcomes of Patients with Giant Hydronephrosis After Pyeloplasty
title_fullStr Long-term Outcomes of Patients with Giant Hydronephrosis After Pyeloplasty
title_full_unstemmed Long-term Outcomes of Patients with Giant Hydronephrosis After Pyeloplasty
title_short Long-term Outcomes of Patients with Giant Hydronephrosis After Pyeloplasty
title_sort long term outcomes of patients with giant hydronephrosis after pyeloplasty
topic differential renal function
poorly functioning kidney
pyeloplasty
ureteropelvic junction obstruction
renal parenchymal thickness
url https://jag.journalagent.com/z4/download_fulltext.asp?pdir=behcetuz&plng=eng&un=BUCHD-79989
work_keys_str_mv AT aysebasakucan longtermoutcomesofpatientswithgianthydronephrosisafterpyeloplasty
AT begumsonmez longtermoutcomesofpatientswithgianthydronephrosisafterpyeloplasty
AT aysedemetpayza longtermoutcomesofpatientswithgianthydronephrosisafterpyeloplasty
AT arzusencan longtermoutcomesofpatientswithgianthydronephrosisafterpyeloplasty