A case report of hermaphrodite goat: clinical and genetic approach
This case report describes clinical examination and cytogenetic and molecular genetic analyses of a hermaphrodite mixed Maltese breed goat that was referred to the Gynecology Clinic of the Faculty of Veterinary Medicine, Selcuk University in 2010. In anamnesis, goat was a single kid at the birth and...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
| Subjects: | |
| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=1054 |
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| Summary: | This case report describes clinical examination and cytogenetic
and molecular genetic analyses of a hermaphrodite
mixed Maltese breed goat that was referred to the Gynecology
Clinic of the Faculty of Veterinary Medicine, Selcuk University
in 2010. In anamnesis, goat was a single kid at the birth
and was polled. Clitoris was 1.9x0.9 cm in size and vagina
was shorter than normal. By palpation and ultrasonographic
examination, it was determined that the right (4.88 cm) and
left (2.87 cm) testicles were located under skin in the inguinal
region. Breast and nipples were in normal size. There
was a rudimentary penis located under skin but no scrotum
or prepitium was observed. After chromosome preparation
using peripheral blood samples and GTG staining, appropriate
metaphases were analyzed using an image analyzer program.
Genomic DNA was isolated from the blood sample. Sexdetermining
region Y (SRY) and amelogenin gene regions
were amplified using polymerase chain reaction (PCR) including
positive and negative controls. In karyotype analysis,
metaphase plaque was observed as 60,XY. In PCR analysis, no
SRY amplification was determined and only AMX allele was
observed for amelogenin locus. Hermaphroditism is widely
observed in goats and a number different mechanisms were
reported. It is suggested that polled rams should be culled
and karyotype and molecular genetics analyses should be
performed to evaluate hermaphrodite cases in detail. |
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| ISSN: | 1309-6958 2146-1953 |