The visual outcomes and corneal biomechanical properties after PRK and SMILE in low to moderate myopia
Purpose: To compare the corneal biomechanical parameters, visual outcome, and epithelial remodeling after small-incision lenticule extraction (SMILE) and photorefractive keratectomy (PRK) for low to moderate myopia. Design: Prospective, interventional, randomized, comparative study. Methods: Eighty...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Indian Journal of Ophthalmology |
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| Online Access: | https://journals.lww.com/10.4103/IJO.IJO_1250_24 |
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| author | Shivani Joshi Aafreen Bari Chetan Shakkarwal Tushar Agarwal Tanuj Dada Rajesh Sinha Jeewan Singh Titiyal Namrata Sharma |
| author_facet | Shivani Joshi Aafreen Bari Chetan Shakkarwal Tushar Agarwal Tanuj Dada Rajesh Sinha Jeewan Singh Titiyal Namrata Sharma |
| author_sort | Shivani Joshi |
| collection | DOAJ |
| description | Purpose:
To compare the corneal biomechanical parameters, visual outcome, and epithelial remodeling after small-incision lenticule extraction (SMILE) and photorefractive keratectomy (PRK) for low to moderate myopia.
Design:
Prospective, interventional, randomized, comparative study.
Methods:
Eighty eyes of 40 patients undergoing bilateral SMILE or PRK for low to moderate myopia (<-5 D SE) were included. They were divided into two groups based on the planned refractive surgery. Visual acuity, corneal biomechanics using Corvis-ST, epithelial mapping via anterior segment optical coherence tomography, and higher-order aberrations were recorded both preoperatively and postoperatively at 6 months and compared.
Results:
At 6 months follow-up, the corrected distance visual acuity as well as the postoperative spherical equivalent of both the groups were comparable (P = 0.13 and P = 0.32, respectively). The biomechanical parameters like deformation amplitude ratio (P < 0.01), inverse concave radius (P = 0.006), integrated ratio (P < 0.01), stress–strain index (P < 0.01), Ambrosio’s relational thickness (ArTH) (P < 0.01), and corneal biomechanical index-laser vision correction (P = 0.02) were altered more in the SMILE group than in the PRK group, while the biomechanically corrected intraocular pressure (P = 0.16) was comparable. Epithelial remodeling (P = 0.59), higher-order aberrations (P = 0.53), and stromal keratocyte loss (P = 0.16) in both the groups were comparable.
Conclusion:
Both SMILE and PRK are comparably effective procedures for correction of low to moderate myopia in terms of visual outcomes; however, the corneal biomechanical stability in PRK is superior than that in SMILE. |
| format | Article |
| id | doaj-art-71f176e0337f4d41a00f975b13140742 |
| institution | Kabale University |
| issn | 0301-4738 1998-3689 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj-art-71f176e0337f4d41a00f975b131407422025-01-07T06:27:42ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892025-01-0173112813310.4103/IJO.IJO_1250_24The visual outcomes and corneal biomechanical properties after PRK and SMILE in low to moderate myopiaShivani JoshiAafreen BariChetan ShakkarwalTushar AgarwalTanuj DadaRajesh SinhaJeewan Singh TitiyalNamrata SharmaPurpose: To compare the corneal biomechanical parameters, visual outcome, and epithelial remodeling after small-incision lenticule extraction (SMILE) and photorefractive keratectomy (PRK) for low to moderate myopia. Design: Prospective, interventional, randomized, comparative study. Methods: Eighty eyes of 40 patients undergoing bilateral SMILE or PRK for low to moderate myopia (<-5 D SE) were included. They were divided into two groups based on the planned refractive surgery. Visual acuity, corneal biomechanics using Corvis-ST, epithelial mapping via anterior segment optical coherence tomography, and higher-order aberrations were recorded both preoperatively and postoperatively at 6 months and compared. Results: At 6 months follow-up, the corrected distance visual acuity as well as the postoperative spherical equivalent of both the groups were comparable (P = 0.13 and P = 0.32, respectively). The biomechanical parameters like deformation amplitude ratio (P < 0.01), inverse concave radius (P = 0.006), integrated ratio (P < 0.01), stress–strain index (P < 0.01), Ambrosio’s relational thickness (ArTH) (P < 0.01), and corneal biomechanical index-laser vision correction (P = 0.02) were altered more in the SMILE group than in the PRK group, while the biomechanically corrected intraocular pressure (P = 0.16) was comparable. Epithelial remodeling (P = 0.59), higher-order aberrations (P = 0.53), and stromal keratocyte loss (P = 0.16) in both the groups were comparable. Conclusion: Both SMILE and PRK are comparably effective procedures for correction of low to moderate myopia in terms of visual outcomes; however, the corneal biomechanical stability in PRK is superior than that in SMILE.https://journals.lww.com/10.4103/IJO.IJO_1250_24corneal biomechanicsmyopiaprksmile |
| spellingShingle | Shivani Joshi Aafreen Bari Chetan Shakkarwal Tushar Agarwal Tanuj Dada Rajesh Sinha Jeewan Singh Titiyal Namrata Sharma The visual outcomes and corneal biomechanical properties after PRK and SMILE in low to moderate myopia Indian Journal of Ophthalmology corneal biomechanics myopia prk smile |
| title | The visual outcomes and corneal biomechanical properties after PRK and SMILE in low to moderate myopia |
| title_full | The visual outcomes and corneal biomechanical properties after PRK and SMILE in low to moderate myopia |
| title_fullStr | The visual outcomes and corneal biomechanical properties after PRK and SMILE in low to moderate myopia |
| title_full_unstemmed | The visual outcomes and corneal biomechanical properties after PRK and SMILE in low to moderate myopia |
| title_short | The visual outcomes and corneal biomechanical properties after PRK and SMILE in low to moderate myopia |
| title_sort | visual outcomes and corneal biomechanical properties after prk and smile in low to moderate myopia |
| topic | corneal biomechanics myopia prk smile |
| url | https://journals.lww.com/10.4103/IJO.IJO_1250_24 |
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