Time to sputum culture conversion as a predictor of cure in multidrug-resistant tuberculosis patients: a multicenter retrospective cohort study in Pakistan

Time to sputum culture conversion as a predictor of cure in multidrug-resistant tuberculosis patients: a multicenter retrospective cohort study in Pakistan

This study aimed to evaluate how the time to sputum culture conversion (SCC) predicts cure and to identify factors associated with delayed SCC and cure among multidrug-resistant tuberculosis (MDR-TB) patients receiving longer treatment regimens of 18-24 months. This multicenter retrospective cohort...

Full description

Saved in:

Bibliographic Details
Main Authors:	Abdul Wahid, Nafees Ahmad, Fahad Saleem, Amjad Khan, Asad Khan, Faiz Ullah Khan, Farman Ullah Khan
Format:	Article
Language:	English
Published:	PAGEPress Publications 2025-04-01
Series:	Monaldi Archives for Chest Disease
Subjects:	Drug resistant-TB longer treatment regimen MDR-TB Pakistan sputum culture conversion tuberculosis
Online Access:	https://www.monaldi-archives.org/macd/article/view/3200
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

The Role of TB-LAMP Method in Detecting Mycobacterium tuberculosis from Sputum of Patients Suspected of Having Pulmonary Tuberculosis
by: Mardiastuti H Wahid, et al.
Published: (2020-12-01)

The Role of TB-LAMP Method in Detecting Mycobacterium tuberculosis from Sputum of Patients Suspected of Having Pulmonary Tuberculosis
by: Mardiastuti H Wahid, et al.
Published: (2020-12-01)

Bridging gaps in tuberculosis control: addressing cross-border challenges between India and Pakistan
by: Harendra Kumar, et al.
Published: (2025-05-01)

The occurrence of multidrug-resistant Mycobacterium tuberculosis from patients of pulmonary tuberculosis
by: Azhar Iqbal, et al.
Published: (2022-04-01)

Analysis of Fungi in the Respiratory Tract of Patients with Tuberculosis at the Palembang Public Health Laboratory Center (BBLKM Palembang)
by: Herry Hermansyah, et al.
Published: (2024-12-01)

Risk Factors for Multidrug-resistant Tuberculosis
by: Cleopas Martin Rumende
Published: (2018-04-01)

Risk Factors for Multidrug-resistant Tuberculosis
by: Cleopas Martin Rumende
Published: (2018-04-01)

Delamanid in the Treatment of MDR/pre-XDR TB in Arkhangelsk Region in 2019–2021
by: E. S. Khimova, et al.
Published: (2023-07-01)

Non-sputum-based triage and confirmatory diagnostic tests for pediatric TB
by: A. Drane, et al.
Published: (2025-03-01)

Operational research as a mechanism to improve treatment outcomes for drug-resistant TB in the WHO European Region
by: G.B. Migliori, et al.
Published: (2024-03-01)

The impact of the war in Ukraine on the prevalence of MDR/RR-TB in Poland
by: A. Nowinski, et al.
Published: (2025-01-01)

Treatment outcomes of extensively drug-resistant tuberculosis in Europe: a retrospective cohort studyResearch in context
by: Yousra Kherabi, et al.
Published: (2025-09-01)

Evaluation of the multiple doses thiozonide’s pharmacokinetics in patients diagnosed with pulmonary tuberculosis with multidrug-resistant or extensively drug-resistant <i>Mycobacterium tuberculosis</i>
by: А. Yu. Savchenko, et al.
Published: (2024-01-01)

Safety of chemotherapy of MDR/XDR-TB patients in high HIV prevalence settings
by: A. V. Kukurika, et al.
Published: (2022-12-01)

Use of the GenoType MTBDRplus for early diagnosis of multidrug-resistant tuberculosis
by: O. M. Raznatovska, et al.
Published: (2017-04-01)

Pyrazinamide Resistance: A Major Cause of Switching Shorter to Longer Bedaquiline-based Regimens in Multidrug-resistant Tuberculosis Patients
by: Oki Nugraha Putra, et al.
Published: (2024-12-01)

TB financing in East Europe promotes unnecessary hospital admissions: the case of Armenia
by: Laura Gillini, et al.
Published: (2013-03-01)

Impacts of MDR/XDR-TB on the global tuberculosis epidemic: Challenges and opportunities
by: Kai Ling Chin, et al.
Published: (2024-01-01)

Global, regional, and national burden and trends of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis in adolescents and adults aged 15–49 years from 2010 to 2021: insights from the global burden of disease study 2021
by: Kunping Cui, et al.
Published: (2025-07-01)

Prevalence and epidemic pattern of ecdemic multidrug-resistant tuberculosis during 2012–2022 in Hangzhou, China: implication for public health strategies
by: Qingchun Li, et al.
Published: (2024-10-01)

Mutational Insights into GyrA and GyrB Genes in Mycobacterium tuberculosis: A Genetic Basis for Fluoroquinolone Resistance in Multidrug-resistant Tuberculosis
by: Anam Shafiq, et al.
Published: (2024-12-01)

NOI ABORDĂRI ÎN TRATAMENTUL TUBERCULOZEI DROGREZISTENTE
by: Евгения КУЛА
Published: (2025-04-01)

The United Nations’ ambitious roadmap against tuberculosis: opportunities, challenges and the imperative of equity
by: Bashar Haruna Gulumbe, et al.
Published: (2024-12-01)

Impact of US funding cuts and stop work orders on TB services and research in South Africa
by: N. Ndjeka, et al.
Published: (2025-04-01)

Progress in programmatic management of drug-resistant TB, WHO Eastern Mediterranean Region, 2018-2023
by: K. Bennani, et al.
Published: (2024-09-01)

A retrospective analysis of tuberculosis in livestock farmers in Lahore district, Pakistan
by: Chanda Jabeen, et al.
Published: (2024-08-01)

Recurrence of tuberculosis and associated risk factors among Non-HIV patients in Taiwan: A retrospective cohort study
by: Che-min Hsu, et al.
Published: (2025-11-01)

BARRIERS TO THE IMPLEMENTATION OF ISONIAZID PREVENTIVE THERAPY AMONG CHILDREN UNDER FIVE YEARS OLD IN CLOSE CONTACT WITH SPUTUM SMEAR-POSITIVE TB PATIENTS
by: Tirsa Hizkia Saverina Nugroho, et al.
Published: (2021-01-01)

Urgent request for pretomanid label expansion to align with WHO guidelines and improve treatment accessibility and efficacy
by: L. Kuksa, et al.
Published: (2025-03-01)

Isoniazid-resistant TB and associated factors in Ethiopia
by: S. Moga, et al.
Published: (2025-06-01)

Is South Africa ready for point-of-care, non-sputum tests for TB diagnosis? An assessment of end-user perceptions on a novel urine test and tongue swab for TB testing
by: Nasiphi Mqedlana-Ntombela, et al.
Published: (2025-08-01)

Secondary Metabolites from a New Antibiotic-Producing Endophytic Streptomyces Isolate Inhibited Pathogenic and Multidrug-Resistant <i>Mycobacterium tuberculosis</i> Strains
by: Govinda Raju Vadankula, et al.
Published: (2025-04-01)

A survey of the effectiveness of centralized consilia in providing advice on drug-resistant TB
by: A. Vasquez, et al.
Published: (2024-07-01)

DESCRIPTION OF THE CAUSES OF MDR-TB AT IBNU SINA HOSPITAL GRESIK
by: Cucuk Rahmadi Purwanto, et al.
Published: (2022-10-01)

Tuberculosis multirresistente en adolescente: A propósito de un caso
by: Lorena García-Agudelo
Published: (2025-02-01)

Efektivitas dan Efek Samping pada Terapi Multi-Drug-Resistant Tuberculosis (MDR-TB): Kajian Literatur
by: Dwi Arymbhi Sanjaya, et al.
Published: (2025-03-01)

To investigate the impact of revised diagnostic algorithm on presentation of multidrug-resistant tuberculosis cases at a referral centre in India
by: Sandeep Jain, et al.
Published: (2024-10-01)

9-12 months short treatment for patients with MDR-TB increases treatment success in Kyrgyzstan
by: Elena Zhdanova, et al.
Published: (2021-09-01)

Prevalence of drug resistance in clinical isolates of tuberculosis from GCC: a literature review from January 2002 to March 2013
by: Mohammed Yahya Areeshi, et al.
Published: (2014-09-01)

Treatment results of patients with multiple and extensive drug resistance registered in 2012 in the Russian Federation and in the world
by: S. A. Sterlikov, et al.
Published: (2016-01-01)