Trends and impacts of SARS-CoV-2 genome sharing: a comparative analysis of China and the global community, 2020–2023

ObjectiveThe global sharing of pathogen genome sequences has been significantly expedited by the COVID-19 pandemic. This study aims to elucidate the global landscape of SARS-CoV-2 genome sharing between 2020 and 2023 with a focus on quantity, timeliness, and quality. Specifically, the characteristic...

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Main Authors: Yenan Feng, Songqi Chen, Anqi Wang, Zhongfu Zhao, Cao Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Public Health
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Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2024.1491623/full
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author Yenan Feng
Songqi Chen
Anqi Wang
Zhongfu Zhao
Cao Chen
author_facet Yenan Feng
Songqi Chen
Anqi Wang
Zhongfu Zhao
Cao Chen
author_sort Yenan Feng
collection DOAJ
description ObjectiveThe global sharing of pathogen genome sequences has been significantly expedited by the COVID-19 pandemic. This study aims to elucidate the global landscape of SARS-CoV-2 genome sharing between 2020 and 2023 with a focus on quantity, timeliness, and quality. Specifically, the characteristics of China are examined.MethodsSARS-CoV-2 genomes along with associated metadata were sourced from GISAID database. The genomes were analyzed to evaluate the quantity, timeliness, and quality across different countries/regions. The metadata characteristics of shared genomes in China in 2023 were examined and compared with the actual demographic data of China in 2023.ResultsFrom 2020 to 2023, European countries consistently maintained high levels of genomic data sharing in terms of quantity, timeliness, and quality. In 2023, China made remarkable improvements in sequence sharing, ranking among the top 3.89% globally for quantity, 22.78% for timeliness, and 17.78% for quality. The genome sharing in China in 2023 covered all provinces with Shanghai Municipality contributing the most genomes. Human samples accounted for 99.73% of the shared genomes and exhibited three distinct peaks in collection dates. Males constituted 52.06%, while females constituted 47.94%. Notably, there was an increase in individuals aged 65 and above within the GISAID database compared to China’s overall population in 2023.ConclusionThe global sharing of SARS-CoV-2 genomes in 2020–2023 exhibited disparities in terms of quantity, timeliness, and quality. However, China has made significant advancements since 2023 by achieving comprehensive coverage across provinces, timely dissemination of data, and widespread population monitoring. Strengthening data sharing capabilities in countries like China during the SARS-CoV-2 pandemic will play a crucial role in containing and responding to future pandemics caused by emerging pathogens.
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spelling doaj-art-71a48beb4cf04c10b2c549991f2b6f442024-11-20T06:26:41ZengFrontiers Media S.A.Frontiers in Public Health2296-25652024-11-011210.3389/fpubh.2024.14916231491623Trends and impacts of SARS-CoV-2 genome sharing: a comparative analysis of China and the global community, 2020–2023Yenan FengSongqi ChenAnqi WangZhongfu ZhaoCao ChenObjectiveThe global sharing of pathogen genome sequences has been significantly expedited by the COVID-19 pandemic. This study aims to elucidate the global landscape of SARS-CoV-2 genome sharing between 2020 and 2023 with a focus on quantity, timeliness, and quality. Specifically, the characteristics of China are examined.MethodsSARS-CoV-2 genomes along with associated metadata were sourced from GISAID database. The genomes were analyzed to evaluate the quantity, timeliness, and quality across different countries/regions. The metadata characteristics of shared genomes in China in 2023 were examined and compared with the actual demographic data of China in 2023.ResultsFrom 2020 to 2023, European countries consistently maintained high levels of genomic data sharing in terms of quantity, timeliness, and quality. In 2023, China made remarkable improvements in sequence sharing, ranking among the top 3.89% globally for quantity, 22.78% for timeliness, and 17.78% for quality. The genome sharing in China in 2023 covered all provinces with Shanghai Municipality contributing the most genomes. Human samples accounted for 99.73% of the shared genomes and exhibited three distinct peaks in collection dates. Males constituted 52.06%, while females constituted 47.94%. Notably, there was an increase in individuals aged 65 and above within the GISAID database compared to China’s overall population in 2023.ConclusionThe global sharing of SARS-CoV-2 genomes in 2020–2023 exhibited disparities in terms of quantity, timeliness, and quality. However, China has made significant advancements since 2023 by achieving comprehensive coverage across provinces, timely dissemination of data, and widespread population monitoring. Strengthening data sharing capabilities in countries like China during the SARS-CoV-2 pandemic will play a crucial role in containing and responding to future pandemics caused by emerging pathogens.https://www.frontiersin.org/articles/10.3389/fpubh.2024.1491623/fullSARS-CoV-2genomic sequencedata sharingGISAIDChina
spellingShingle Yenan Feng
Songqi Chen
Anqi Wang
Zhongfu Zhao
Cao Chen
Trends and impacts of SARS-CoV-2 genome sharing: a comparative analysis of China and the global community, 2020–2023
Frontiers in Public Health
SARS-CoV-2
genomic sequence
data sharing
GISAID
China
title Trends and impacts of SARS-CoV-2 genome sharing: a comparative analysis of China and the global community, 2020–2023
title_full Trends and impacts of SARS-CoV-2 genome sharing: a comparative analysis of China and the global community, 2020–2023
title_fullStr Trends and impacts of SARS-CoV-2 genome sharing: a comparative analysis of China and the global community, 2020–2023
title_full_unstemmed Trends and impacts of SARS-CoV-2 genome sharing: a comparative analysis of China and the global community, 2020–2023
title_short Trends and impacts of SARS-CoV-2 genome sharing: a comparative analysis of China and the global community, 2020–2023
title_sort trends and impacts of sars cov 2 genome sharing a comparative analysis of china and the global community 2020 2023
topic SARS-CoV-2
genomic sequence
data sharing
GISAID
China
url https://www.frontiersin.org/articles/10.3389/fpubh.2024.1491623/full
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