Vulvar squamous cell carcinoma: The role of p53 and p16 immunohistochemistry

Vulvar squamous cell carcinoma: The role of p53 and p16 immunohistochemistry

Vulvar squamous cell carcinomas (SCC) represent a heterogeneous group of patients with implications for prognosis and response to treatment. Human papillomavirus (HPV)-associated SCC is characterised by p16 positivity, whereas non-HPV SCC often shows aberrant p53 expression. We conducted a retrospec...

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Bibliographic Details
Main Authors: Helena M Obermair, James Elhindi, Alison Brand, Unine Herbst
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Gynecologic Oncology Reports
Subjects:
Vulva cancer
pre-invasive disease
immunohistochemistry
molecular pathology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578924002236
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