Paraclinical Characteristics of Fatal and Recovered COVID-19 Cases: a Retrospective Study

Introduction: COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-Cov2). It is a potentially deadly disease with grave consequences for public and global health. This study compared laboratory indices in recovered and fatal COVID-19 cases. Methods: In this descriptiveanaly...

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Main Authors: Elham Goodarzi1, Mohammad Kakavand2, Kobra Rashidi3, Shahram Mamdohi2, Victoria Momenabadi4, Mojgan Navabi2, Hamidreza Abolfathi2, Zaher Khazaei5
Format: Article
Language:English
Published: Pasteur Institute of Iran 2022-06-01
Series:Journal of Medical Microbiology and Infectious Diseases
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author Elham Goodarzi1
Mohammad Kakavand2
Kobra Rashidi3
Shahram Mamdohi2
Victoria Momenabadi4
Mojgan Navabi2
Hamidreza Abolfathi2
Zaher Khazaei5
author_facet Elham Goodarzi1
Mohammad Kakavand2
Kobra Rashidi3
Shahram Mamdohi2
Victoria Momenabadi4
Mojgan Navabi2
Hamidreza Abolfathi2
Zaher Khazaei5
author_sort Elham Goodarzi1
collection DOAJ
description Introduction: COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-Cov2). It is a potentially deadly disease with grave consequences for public and global health. This study compared laboratory indices in recovered and fatal COVID-19 cases. Methods: In this descriptiveanalytical cross-sectional study, sampling was conducted using the total count method, and the data was collected from the Borujerd Health Network's Disease Management Center database. From February 20, 2020, to July 21, 2020, 380 patients with positive PCR tests were included. The extracted data was exported into Stata-14 software. To analyze descriptive objectives, mean, percentage, standard deviation, Chi-squared test, and t-test were used. Results: Out of 380 positive COVID-19 cases, 300 patients recovered, and 80 lost their life. More than half of the recovered and fatal cases were men (55.16%). The highest mortality rate belonged to 80 ≤ years (27.5%). Among fatal cases, 38.75% had no underlying disease, and the most common underlying diseases were diabetes (27.5%), chronic hypertension (18.75%), and malignancy (7.5%). Comparison of laboratory indices revealed a significant difference in the mean LHD, Na, K, BUN, BS, PT, AST, ALT, ALP, and ALP Hb between recovered and fatal cases (P <0.05). Conclusion: This finding can help determine patients' prognoses and adjust the treatment approach. Further studies on paraclinical characteristics will shed further light on the pathogenesis of COVID-19 and appropriate treatment measures.
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publisher Pasteur Institute of Iran
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spelling doaj-art-716d0c8b5a8e46c8a2daafb8fb824ab02025-08-20T03:52:52ZengPasteur Institute of IranJournal of Medical Microbiology and Infectious Diseases2345-53492345-53302022-06-01102808610.52547/JoMMID.10.2.80Paraclinical Characteristics of Fatal and Recovered COVID-19 Cases: a Retrospective StudyElham Goodarzi10Mohammad Kakavand21https://orcid.org/0000-0003-0748-8507Kobra Rashidi32https://orcid.org/0000-0002-2230-3577Shahram Mamdohi23https://orcid.org/0000-0002-0739-8993Victoria Momenabadi44https://orcid.org/0000-0002-9265-7100Mojgan Navabi25Hamidreza Abolfathi26Zaher Khazaei57https://orcid.org/0000-0001-8619-36641Social Determinants of Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran2Deputy of Health, Lorestan University of Medical Sciences, Khorramabad, Iran3Nursing Faculty of Borujerd, Lorestan University of Medical Sciences, Khorramabad, Iran2Deputy of Health, Lorestan University of Medical Sciences, Khorramabad, Iran4Department of Public Health, School of Health, Bam University of Medical Sciences, Bam, Iran2Deputy of Health, Lorestan University of Medical Sciences, Khorramabad, Iran2Deputy of Health, Lorestan University of Medical Sciences, Khorramabad, Iran5Nahavand School of Allied Medical Sciences, Hamadan University of Medical Sciences, Hamadan, IranIntroduction: COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-Cov2). It is a potentially deadly disease with grave consequences for public and global health. This study compared laboratory indices in recovered and fatal COVID-19 cases. Methods: In this descriptiveanalytical cross-sectional study, sampling was conducted using the total count method, and the data was collected from the Borujerd Health Network's Disease Management Center database. From February 20, 2020, to July 21, 2020, 380 patients with positive PCR tests were included. The extracted data was exported into Stata-14 software. To analyze descriptive objectives, mean, percentage, standard deviation, Chi-squared test, and t-test were used. Results: Out of 380 positive COVID-19 cases, 300 patients recovered, and 80 lost their life. More than half of the recovered and fatal cases were men (55.16%). The highest mortality rate belonged to 80 ≤ years (27.5%). Among fatal cases, 38.75% had no underlying disease, and the most common underlying diseases were diabetes (27.5%), chronic hypertension (18.75%), and malignancy (7.5%). Comparison of laboratory indices revealed a significant difference in the mean LHD, Na, K, BUN, BS, PT, AST, ALT, ALP, and ALP Hb between recovered and fatal cases (P <0.05). Conclusion: This finding can help determine patients' prognoses and adjust the treatment approach. Further studies on paraclinical characteristics will shed further light on the pathogenesis of COVID-19 and appropriate treatment measures.coronavirus disease 2019 (covid-19)mortalityrecoveryparaclinical characteristics
spellingShingle Elham Goodarzi1
Mohammad Kakavand2
Kobra Rashidi3
Shahram Mamdohi2
Victoria Momenabadi4
Mojgan Navabi2
Hamidreza Abolfathi2
Zaher Khazaei5
Paraclinical Characteristics of Fatal and Recovered COVID-19 Cases: a Retrospective Study
Journal of Medical Microbiology and Infectious Diseases
coronavirus disease 2019 (covid-19)
mortality
recovery
paraclinical characteristics
title Paraclinical Characteristics of Fatal and Recovered COVID-19 Cases: a Retrospective Study
title_full Paraclinical Characteristics of Fatal and Recovered COVID-19 Cases: a Retrospective Study
title_fullStr Paraclinical Characteristics of Fatal and Recovered COVID-19 Cases: a Retrospective Study
title_full_unstemmed Paraclinical Characteristics of Fatal and Recovered COVID-19 Cases: a Retrospective Study
title_short Paraclinical Characteristics of Fatal and Recovered COVID-19 Cases: a Retrospective Study
title_sort paraclinical characteristics of fatal and recovered covid 19 cases a retrospective study
topic coronavirus disease 2019 (covid-19)
mortality
recovery
paraclinical characteristics
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