Effects of Cannabidiol and a Novel Cannabidiol Analog against Tactile Allodynia in a Murine Model of Cisplatin-Induced Neuropathy: Enhanced Effects of Sub-Analgesic Doses of Morphine

Effects of Cannabidiol and a Novel Cannabidiol Analog against Tactile Allodynia in a Murine Model of Cisplatin-Induced Neuropathy: Enhanced Effects of Sub-Analgesic Doses of Morphine

Objective: This research examined whether a cannabidiol (CBD)-opioid pharmacotherapy could attenuate cisplatin-induced tactile allodynia. Methods: Mice (C57BL/6) were given 6 doses of 2.3 mg/kg cisplatin intraperitoneally (IP) on alternating days to induce tactile allodynia as quantified...

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Bibliographic Details
Main Authors: Hannah Marie Harris, Waseem Gul, Mahmoud A. ElSohly, Kenneth J. Sufka
Format: Article
Language:English
Published: Karger Publishers 2018-06-01
Series:Medical Cannabis and Cannabinoids
Online Access:https://karger.com/article/doi/10.1159/000489077
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