Structural insights into the initiation of free radical formation in the Class Ib ribonucleotide reductases in Mycobacteria

Class I ribonucleotide reductases consisting of α and β subunits convert ribonucleoside diphosphates to deoxyribonucleoside diphosphates involving an intricate free radical mechanism. The generation of free radicals in the Class Ib ribonucleotide reductases is mediated by di-manganese ions in the β...

Full description

Saved in:
Bibliographic Details
Main Authors: Lumbini R. Yadav, Vasudha Sharma, Maheswaran Shanmugam, Shekhar C. Mande
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Current Research in Structural Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2665928X24000345
Tags: Add Tag
No Tags, Be the first to tag this record!