Examining the independent and moderating effects of arterial stiffness and cerebral blood flow on total hippocampal and hippocampal subfield volumes

Examining the independent and moderating effects of arterial stiffness and cerebral blood flow on total hippocampal and hippocampal subfield volumes

IntroductionThere is a critical link between vascular disease and the progression to dementia. The hippocampus has been implicated in memory and cognitive decline. In this study, we investigate the independent and moderating effects of increased arterial stiffness (AS) and reduced cerebral blood flo...

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Bibliographic Details
Main Authors: Michelle Horan, Daniel Carey, Silvin Knight, A. Fagan, James F. M. Meaney, Rose Anne Kenny, Céline De Looze
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
cognitive impairment
arterial stiffening
cerebral blood flow
hippocampus
hippocampal subfield atrophy
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2025.1466294/full
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