Cognitive impairment is associated with female sex, low level of education, lack of spousal relationship, and serum testosterone in type 2 diabetes
Background: Relationship between cognitive impairment, serum testosterone, and body mass index in type 2 diabetes (T2D) is not fully understood. Objectives: To compare cognition between T2D patients and healthy controls. To determine relationship of mild cognitive impairment (MCI) with serum total...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-05-01
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| Series: | Annals of Medical Science and Research |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/amsr.amsr_8_24 |
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| Summary: | Background:
Relationship between cognitive impairment, serum testosterone, and body mass index in type 2 diabetes (T2D) is not fully understood.
Objectives:
To compare cognition between T2D patients and healthy controls. To determine relationship of mild cognitive impairment (MCI) with serum total testosterone and sociodemographic factors.
Materials and Methods:
The study was a cross-sectional case-control study. About 17 male and female T2D patients and healthy controls were randomly selected. Montreal cognitive assessment-basic (MoCA-B) was used to assess cognition; anthropometric indices were measured using standard protocols, while total testosterone was assayed from serum using competitive ELISA kits.
Results:
The mean age of the T2D patients and healthy controls was 51.62 and 66.76 years, respectively. About 82.35% of the T2D patients had MCI compared to 58.82% of the healthy controls. MCI was associated with female sex (P = 0.033), lack of spousal relationship (P = 0.016), low level of education (P = 0.014), and normal or high level of total testosterone (P = 0.010).
Conclusion:
Proportion of MCI in T2D patients is high and is associated with female sex, lack of spousal relationship, low level of education, and normal or high testosterone level. |
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| ISSN: | 2949-785X 2949-7868 |