Poly-ether-ether-ketone wear particles induce a pro-inflammatory phenotype in a human monocytic cell line

Poly-ether-ether-ketone wear particles induce a pro-inflammatory phenotype in a human monocytic cell line

ObjectivesThe aim of this study was to assess potential pro-inflammatory responses induced in a human monocyte cell line by poly-ether-ether-ketone (PEEK) particles. Investigations also focussed on the role of toll-like receptor 4 (TLR4) and reactive oxygen species (ROS) in immune responses to PEEK....

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Bibliographic Details
Main Authors: Shannon Jamieson, Philip Hyde, Patrick Card, David Deehan, John Kirby, Alison Tyson-Capper
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
chemokines
macrophages
immunology
osteoarthritis
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1507248/full
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