Selenium nanoparticles modified niobium MXene for non-enzymatic detection of glucose

Abstract Glucose sensing remains a crucial need as diabetes is a worldwide concern. This work reports the application of Nb2CT x —selenium nanoparticle composite material for the nonenzymatic sensing of glucose. The surface morphology of the synthesized composite was analyzed using various microscop...

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Main Authors: Prabisha K. E., Neena P. K., Menon Ankitha, P. Abdul Rasheed, P. V. Suneesh, T. G. Satheesh Babu
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-85748-y
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author Prabisha K. E.
Neena P. K.
Menon Ankitha
P. Abdul Rasheed
P. V. Suneesh
T. G. Satheesh Babu
author_facet Prabisha K. E.
Neena P. K.
Menon Ankitha
P. Abdul Rasheed
P. V. Suneesh
T. G. Satheesh Babu
author_sort Prabisha K. E.
collection DOAJ
description Abstract Glucose sensing remains a crucial need as diabetes is a worldwide concern. This work reports the application of Nb2CT x —selenium nanoparticle composite material for the nonenzymatic sensing of glucose. The surface morphology of the synthesized composite was analyzed using various microscopic techniques like scanning electron microscopy, transmission electron microscopy, and its structural properties were analyzed using diffraction and spectroscopic methods. A gold disc electrode was modified using the nanocomposite and tested for glucose in an alkaline medium. The sensing was based on the oxidation of glucose on the catalytic surface. The glucose was quantified amperometrically at a significantly lower overpotential of 0.16 V. The sensor showed a good detection range from 2 to 30 mM with a sensitivity of 4.15 µA mM−1 cm−2 and a detection limit of 1.1 mM.
format Article
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institution Kabale University
issn 2045-2322
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publishDate 2025-01-01
publisher Nature Portfolio
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spelling doaj-art-704938c104134f4286c6be2bbb56d1032025-01-12T12:23:40ZengNature PortfolioScientific Reports2045-23222025-01-011511910.1038/s41598-025-85748-ySelenium nanoparticles modified niobium MXene for non-enzymatic detection of glucosePrabisha K. E.0Neena P. K.1Menon Ankitha2P. Abdul Rasheed3P. V. Suneesh4T. G. Satheesh Babu5Department of Chemistry, Amrita School of Physical Sciences Coimbatore, Amrita Vishwa VidyapeethamDepartment of Chemistry, Amrita School of Physical Sciences Coimbatore, Amrita Vishwa VidyapeethamDepartment of Chemistry, Indian Institute of TechnologyDepartment of Chemistry, Indian Institute of TechnologyDepartment of Chemistry, Amrita School of Physical Sciences Coimbatore, Amrita Vishwa VidyapeethamDepartment of Chemistry, Amrita School of Physical Sciences Coimbatore, Amrita Vishwa VidyapeethamAbstract Glucose sensing remains a crucial need as diabetes is a worldwide concern. This work reports the application of Nb2CT x —selenium nanoparticle composite material for the nonenzymatic sensing of glucose. The surface morphology of the synthesized composite was analyzed using various microscopic techniques like scanning electron microscopy, transmission electron microscopy, and its structural properties were analyzed using diffraction and spectroscopic methods. A gold disc electrode was modified using the nanocomposite and tested for glucose in an alkaline medium. The sensing was based on the oxidation of glucose on the catalytic surface. The glucose was quantified amperometrically at a significantly lower overpotential of 0.16 V. The sensor showed a good detection range from 2 to 30 mM with a sensitivity of 4.15 µA mM−1 cm−2 and a detection limit of 1.1 mM.https://doi.org/10.1038/s41598-025-85748-y2D nanomaterialsNb2CTx-MXenesGlucoseAmperometrySelenium nanoparticles
spellingShingle Prabisha K. E.
Neena P. K.
Menon Ankitha
P. Abdul Rasheed
P. V. Suneesh
T. G. Satheesh Babu
Selenium nanoparticles modified niobium MXene for non-enzymatic detection of glucose
Scientific Reports
2D nanomaterials
Nb2CTx-MXenes
Glucose
Amperometry
Selenium nanoparticles
title Selenium nanoparticles modified niobium MXene for non-enzymatic detection of glucose
title_full Selenium nanoparticles modified niobium MXene for non-enzymatic detection of glucose
title_fullStr Selenium nanoparticles modified niobium MXene for non-enzymatic detection of glucose
title_full_unstemmed Selenium nanoparticles modified niobium MXene for non-enzymatic detection of glucose
title_short Selenium nanoparticles modified niobium MXene for non-enzymatic detection of glucose
title_sort selenium nanoparticles modified niobium mxene for non enzymatic detection of glucose
topic 2D nanomaterials
Nb2CTx-MXenes
Glucose
Amperometry
Selenium nanoparticles
url https://doi.org/10.1038/s41598-025-85748-y
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AT pabdulrasheed seleniumnanoparticlesmodifiedniobiummxenefornonenzymaticdetectionofglucose
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