Treatment of Bullous Pemphigoid with Avdoralimab: Multicenter, Randomized, Open-Labeled Phase 2 Study

Treatment of Bullous Pemphigoid with Avdoralimab: Multicenter, Randomized, Open-Labeled Phase 2 Study

Rationale: Experimental data support the role for C5a–C5aR1 axis activation in bullous pemphigoid. We assessed the efficacy and safety of avdoralimab, a specific anti-C5aR1 mAb, for treating bullous pemphigoid. Methods: We conducted a phase 2 open-labeled randomized multicenter study. Patients with...

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Bibliographic Details
Main Authors: Thierry Passeron, Eric Fontas, Thierry Boye, Marie-Aleth Richard, Emmanuel Delaporte, Olivier Dereure
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:JID Innovations
Subjects:
Avdoralimab
Bullous pemphigoid
C5aR1
Online Access:http://www.sciencedirect.com/science/article/pii/S2667026724000547
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