The promise and challenges of pharmacogenomics in psychiatry
Pharmacogenomics (PGx) is an expanding field within precision medicine that is poised to play a crucial role in optimising patient outcomes, particularly in the realm of psychiatry. The remission rate for the initial antidepressant prescribed in the Sequenced Treatment Alternatives to Relieve Depre...
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| Format: | Article |
| Language: | English |
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Academy of Medicine Singapore
2024-12-01
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| Series: | Annals, Academy of Medicine, Singapore |
| Online Access: | https://annals.edu.sg/the-promise-and-challenges-of-pharmacogenomics-in-psychiatry/ |
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| _version_ | 1841544082042650624 |
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| author | Elaine Ah Gi Lo Yi Min Wan Cyrus Su Hui Ho |
| author_facet | Elaine Ah Gi Lo Yi Min Wan Cyrus Su Hui Ho |
| author_sort | Elaine Ah Gi Lo |
| collection | DOAJ |
| description |
Pharmacogenomics (PGx) is an expanding field within precision medicine that is poised to play a crucial role in optimising patient outcomes, particularly in the realm of psychiatry. The remission rate for the initial antidepressant prescribed in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial was only approximately 30%, underscoring the need for more personalised approaches to prescribing.1 For psychiatric patients who may show resistance towards pharmacotherapy, PGx offers promise in reducing adverse effects and enhancing therapeutic efficacy. Personalised pharmacotherapy provides reassurance and potentially mitigates the nocebo effects and somatic symptom exacerbation that are prevalent among these patients. |
| format | Article |
| id | doaj-art-7017be36d5ce41f9953e99f40a8f8b56 |
| institution | Kabale University |
| issn | 2972-4066 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Academy of Medicine Singapore |
| record_format | Article |
| series | Annals, Academy of Medicine, Singapore |
| spelling | doaj-art-7017be36d5ce41f9953e99f40a8f8b562025-01-13T03:06:11ZengAcademy of Medicine SingaporeAnnals, Academy of Medicine, Singapore2972-40662024-12-01531271071210.47102/annals-acadmedsg.2024367The promise and challenges of pharmacogenomics in psychiatryElaine Ah Gi LoYi Min WanCyrus Su Hui Ho Pharmacogenomics (PGx) is an expanding field within precision medicine that is poised to play a crucial role in optimising patient outcomes, particularly in the realm of psychiatry. The remission rate for the initial antidepressant prescribed in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial was only approximately 30%, underscoring the need for more personalised approaches to prescribing.1 For psychiatric patients who may show resistance towards pharmacotherapy, PGx offers promise in reducing adverse effects and enhancing therapeutic efficacy. Personalised pharmacotherapy provides reassurance and potentially mitigates the nocebo effects and somatic symptom exacerbation that are prevalent among these patients.https://annals.edu.sg/the-promise-and-challenges-of-pharmacogenomics-in-psychiatry/ |
| spellingShingle | Elaine Ah Gi Lo Yi Min Wan Cyrus Su Hui Ho The promise and challenges of pharmacogenomics in psychiatry Annals, Academy of Medicine, Singapore |
| title | The promise and challenges of pharmacogenomics in psychiatry |
| title_full | The promise and challenges of pharmacogenomics in psychiatry |
| title_fullStr | The promise and challenges of pharmacogenomics in psychiatry |
| title_full_unstemmed | The promise and challenges of pharmacogenomics in psychiatry |
| title_short | The promise and challenges of pharmacogenomics in psychiatry |
| title_sort | promise and challenges of pharmacogenomics in psychiatry |
| url | https://annals.edu.sg/the-promise-and-challenges-of-pharmacogenomics-in-psychiatry/ |
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