GROWTH PARAMETERS AND VITAMIN D STATUS IN CHILDREN WITH THALASSEMIA MAJOR IN UPPER EGYPT.
Aim: the aim of this study is to assess the growth parameters, vitamin D, calcium, and phosphorous status in children with thalassemia major receiving packed red cells transfusion with chelation therapy. Patients and Methods: In a case control study, 100 patients with beta thalassemia major (aged f...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2014-08-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
| Online Access: | https://mjhid.org/index.php/mjhid/article/view/1768 |
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| _version_ | 1846095589173886976 |
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| author | Fahim M. Fahim Khaled Saad |
| author_facet | Fahim M. Fahim Khaled Saad |
| author_sort | Fahim M. Fahim |
| collection | DOAJ |
| description | Aim: the aim of this study is to assess the growth parameters, vitamin D, calcium, and phosphorous status in children with thalassemia major receiving packed red cells transfusion with chelation therapy.
Patients and Methods: In a case control study, 100 patients with beta thalassemia major (aged from 4 to 15 years) were compared with 100 sex- and age-matched children serves as a control group. Anthropometric measurement, Serum level of calcium, phosphorus and vitamin D (25 hydroxycholecalciferol) were estimated for all patients & controls.
Results: 49% of our patients had short stature. 47% were underweight. BMI of 43 (43%) patients were low. The mean total serum calcium (6.6±1.2 mg/dl) and 25-hydroxycholecalciferol (25-OH Vit D) (10.4±4.6 mcg/dl) levels were significantly lower in our patients than in controls (10.2±1.06 mg/dl and 40.2±12.3 mcg/dl, respectively); each P< 0.001.
Conclusion: Children with beta thalassemia major have delayed growth and metabolic abnormalities that signify the importance of therapeutic interventions. The presence of these abnormalities may be due to iron overload and poor nutritional support.
Keywords: Thalassemia major, Calcium, Growth, vitamin D. |
| format | Article |
| id | doaj-art-700165af34bb4ba69d7b886f7d87818f |
| institution | Kabale University |
| issn | 2035-3006 |
| language | English |
| publishDate | 2014-08-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-700165af34bb4ba69d7b886f7d87818f2025-01-02T10:18:56ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062014-08-011GROWTH PARAMETERS AND VITAMIN D STATUS IN CHILDREN WITH THALASSEMIA MAJOR IN UPPER EGYPT.Fahim M. FahimKhaled SaadAim: the aim of this study is to assess the growth parameters, vitamin D, calcium, and phosphorous status in children with thalassemia major receiving packed red cells transfusion with chelation therapy. Patients and Methods: In a case control study, 100 patients with beta thalassemia major (aged from 4 to 15 years) were compared with 100 sex- and age-matched children serves as a control group. Anthropometric measurement, Serum level of calcium, phosphorus and vitamin D (25 hydroxycholecalciferol) were estimated for all patients & controls. Results: 49% of our patients had short stature. 47% were underweight. BMI of 43 (43%) patients were low. The mean total serum calcium (6.6±1.2 mg/dl) and 25-hydroxycholecalciferol (25-OH Vit D) (10.4±4.6 mcg/dl) levels were significantly lower in our patients than in controls (10.2±1.06 mg/dl and 40.2±12.3 mcg/dl, respectively); each P< 0.001. Conclusion: Children with beta thalassemia major have delayed growth and metabolic abnormalities that signify the importance of therapeutic interventions. The presence of these abnormalities may be due to iron overload and poor nutritional support. Keywords: Thalassemia major, Calcium, Growth, vitamin D.https://mjhid.org/index.php/mjhid/article/view/1768 |
| spellingShingle | Fahim M. Fahim Khaled Saad GROWTH PARAMETERS AND VITAMIN D STATUS IN CHILDREN WITH THALASSEMIA MAJOR IN UPPER EGYPT. Mediterranean Journal of Hematology and Infectious Diseases |
| title | GROWTH PARAMETERS AND VITAMIN D STATUS IN CHILDREN WITH THALASSEMIA MAJOR IN UPPER EGYPT. |
| title_full | GROWTH PARAMETERS AND VITAMIN D STATUS IN CHILDREN WITH THALASSEMIA MAJOR IN UPPER EGYPT. |
| title_fullStr | GROWTH PARAMETERS AND VITAMIN D STATUS IN CHILDREN WITH THALASSEMIA MAJOR IN UPPER EGYPT. |
| title_full_unstemmed | GROWTH PARAMETERS AND VITAMIN D STATUS IN CHILDREN WITH THALASSEMIA MAJOR IN UPPER EGYPT. |
| title_short | GROWTH PARAMETERS AND VITAMIN D STATUS IN CHILDREN WITH THALASSEMIA MAJOR IN UPPER EGYPT. |
| title_sort | growth parameters and vitamin d status in children with thalassemia major in upper egypt |
| url | https://mjhid.org/index.php/mjhid/article/view/1768 |
| work_keys_str_mv | AT fahimmfahim growthparametersandvitamindstatusinchildrenwiththalassemiamajorinupperegypt AT khaledsaad growthparametersandvitamindstatusinchildrenwiththalassemiamajorinupperegypt |