Seroprevalence of Helicobacter pylori in a population of 15 to 35 years old in Mashhad
Background and Objectives: Helicobacter pylori (H. pylori) is a bacterium involved in gastrointestinal disorders with a high prevalence in Iran. We have determined the seroprevalence of H. pylori in the young adult population of Mashhad city for the first time. Materials and Methods: We carried out...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2024-12-01
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| Series: | Iranian Journal of Microbiology |
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| Online Access: | https://ijm.tums.ac.ir/index.php/ijm/article/view/4347 |
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| author | Mahdieh Khoshakhlagh Mohammadreza Tarahomi Fatemeh Asgharian Arghavan Kamali Safoora Sa'd Abadi Kimia Jafarpour Samaneh Abolbashari Mojtaba Meshkat Aida Gholoobi |
| author_facet | Mahdieh Khoshakhlagh Mohammadreza Tarahomi Fatemeh Asgharian Arghavan Kamali Safoora Sa'd Abadi Kimia Jafarpour Samaneh Abolbashari Mojtaba Meshkat Aida Gholoobi |
| author_sort | Mahdieh Khoshakhlagh |
| collection | DOAJ |
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Background and Objectives: Helicobacter pylori (H. pylori) is a bacterium involved in gastrointestinal disorders with a high prevalence in Iran. We have determined the seroprevalence of H. pylori in the young adult population of Mashhad city for the first time.
Materials and Methods: We carried out a cross-sectional study on 933 individuals between the ages of 15 and 35 in Mashhad. The serum level of IgG, IgM, and IgA H. pylori antibodies was determined using enzyme linked immunosorbent assay (ELISA) method.
Results: The average age of the participants including 290 (31.0%) male and 643 (68.9%) female cases was 25.47 ± 5.76. H. pylori IgG was seropositive in 365 (39.1%) of subjects. Occupation (p=0.002), body mass index (p=0.002), marital status (p<0.0001), and age (p<0.007) were meaningfully related to H. pylori IgG seropositivity. Other factors such as sex, educational attainment, history of chronic diseases, and smoking cigarette had no significant relationship with the presence of H. pylori antibodies.
Conclusion: The seroprevalence of H. pylori IgG antibodies in Mashhad's 15 to 35 years old citizens was determined 39.1%. We suggest further studies with larger sample sizes and different age groups as the target population.
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| format | Article |
| id | doaj-art-6f28cee3e1d0433e907a276f8097903f |
| institution | Kabale University |
| issn | 2008-3289 2008-4447 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Microbiology |
| spelling | doaj-art-6f28cee3e1d0433e907a276f8097903f2025-01-06T08:38:46ZengTehran University of Medical SciencesIranian Journal of Microbiology2008-32892008-44472024-12-0116610.18502/ijm.v16i6.17255Seroprevalence of Helicobacter pylori in a population of 15 to 35 years old in MashhadMahdieh Khoshakhlagh0Mohammadreza Tarahomi1Fatemeh Asgharian2Arghavan Kamali3Safoora Sa'd Abadi4Kimia Jafarpour5Samaneh Abolbashari6Mojtaba Meshkat7Aida Gholoobi8Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranStudent Research Committee, Mashhad University of Medical Sciences, Mashhad, IranStudent Research Committee, Mashhad University of Medical Sciences, Mashhad, IranStudent Research Committee, Mashhad University of Medical Sciences, Mashhad, IranStudent Research Committee, Mashhad University of Medical Sciences, Mashhad, IranStudent Research Committee, Mashhad University of Medical Sciences, Mashhad, IranAntimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Community Medicine, Faculty of Medicine, Mashhad Medical Sciences, Islamic Azad University, Mashhad, IranMedical Genetics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Background and Objectives: Helicobacter pylori (H. pylori) is a bacterium involved in gastrointestinal disorders with a high prevalence in Iran. We have determined the seroprevalence of H. pylori in the young adult population of Mashhad city for the first time. Materials and Methods: We carried out a cross-sectional study on 933 individuals between the ages of 15 and 35 in Mashhad. The serum level of IgG, IgM, and IgA H. pylori antibodies was determined using enzyme linked immunosorbent assay (ELISA) method. Results: The average age of the participants including 290 (31.0%) male and 643 (68.9%) female cases was 25.47 ± 5.76. H. pylori IgG was seropositive in 365 (39.1%) of subjects. Occupation (p=0.002), body mass index (p=0.002), marital status (p<0.0001), and age (p<0.007) were meaningfully related to H. pylori IgG seropositivity. Other factors such as sex, educational attainment, history of chronic diseases, and smoking cigarette had no significant relationship with the presence of H. pylori antibodies. Conclusion: The seroprevalence of H. pylori IgG antibodies in Mashhad's 15 to 35 years old citizens was determined 39.1%. We suggest further studies with larger sample sizes and different age groups as the target population. https://ijm.tums.ac.ir/index.php/ijm/article/view/4347Prevalence;Seroepidemiologic studies;Helicobacter pylori;Iran;Young adult |
| spellingShingle | Mahdieh Khoshakhlagh Mohammadreza Tarahomi Fatemeh Asgharian Arghavan Kamali Safoora Sa'd Abadi Kimia Jafarpour Samaneh Abolbashari Mojtaba Meshkat Aida Gholoobi Seroprevalence of Helicobacter pylori in a population of 15 to 35 years old in Mashhad Iranian Journal of Microbiology Prevalence; Seroepidemiologic studies; Helicobacter pylori; Iran; Young adult |
| title | Seroprevalence of Helicobacter pylori in a population of 15 to 35 years old in Mashhad |
| title_full | Seroprevalence of Helicobacter pylori in a population of 15 to 35 years old in Mashhad |
| title_fullStr | Seroprevalence of Helicobacter pylori in a population of 15 to 35 years old in Mashhad |
| title_full_unstemmed | Seroprevalence of Helicobacter pylori in a population of 15 to 35 years old in Mashhad |
| title_short | Seroprevalence of Helicobacter pylori in a population of 15 to 35 years old in Mashhad |
| title_sort | seroprevalence of helicobacter pylori in a population of 15 to 35 years old in mashhad |
| topic | Prevalence; Seroepidemiologic studies; Helicobacter pylori; Iran; Young adult |
| url | https://ijm.tums.ac.ir/index.php/ijm/article/view/4347 |
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