Amiodarone in cardiac transplant waiting list patients with severe heart failure

Heart transplantation is the «gold standard» of severe heart failure treatment. Sudden arrhythmic death is the leading cause of death among these patients. Amiodarone is the only antiarrhythmic drug with beneficial effect on survival of patients with end-stage heart failure. Given its long half-life...

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Main Authors: N. N. Koloskova, V. N. Poptsov, G. M. Salikhova
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2017-06-01
Series:Вестник трансплантологии и искусственных органов
Subjects:
Online Access:https://journal.transpl.ru/vtio/article/view/761
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author N. N. Koloskova
V. N. Poptsov
G. M. Salikhova
author_facet N. N. Koloskova
V. N. Poptsov
G. M. Salikhova
author_sort N. N. Koloskova
collection DOAJ
description Heart transplantation is the «gold standard» of severe heart failure treatment. Sudden arrhythmic death is the leading cause of death among these patients. Amiodarone is the only antiarrhythmic drug with beneficial effect on survival of patients with end-stage heart failure. Given its long half-life, pre-transplant use of amiodarone has been extensively discussed focusing on divergent results regarding morbidity and mortality after heart transplantation. Its adverse clinical events after transplantation remain debatable. This review is aimed at evaluation of the impact of amiodarone pretransplant use on mortality and complications after heart transplantation.
format Article
id doaj-art-6f0f56a3c0b640e5a44b4831236dafb1
institution Kabale University
issn 1995-1191
language Russian
publishDate 2017-06-01
publisher Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
record_format Article
series Вестник трансплантологии и искусственных органов
spelling doaj-art-6f0f56a3c0b640e5a44b4831236dafb12025-08-20T03:44:23ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912017-06-0119213313810.15825/1995-1191-2017-2-133-138632Amiodarone in cardiac transplant waiting list patients with severe heart failureN. N. Koloskova0V. N. Poptsov1G. M. Salikhova2V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian FederationV.I. Shumakov Federal Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian FederationV.I. Shumakov Federal Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian FederationHeart transplantation is the «gold standard» of severe heart failure treatment. Sudden arrhythmic death is the leading cause of death among these patients. Amiodarone is the only antiarrhythmic drug with beneficial effect on survival of patients with end-stage heart failure. Given its long half-life, pre-transplant use of amiodarone has been extensively discussed focusing on divergent results regarding morbidity and mortality after heart transplantation. Its adverse clinical events after transplantation remain debatable. This review is aimed at evaluation of the impact of amiodarone pretransplant use on mortality and complications after heart transplantation.https://journal.transpl.ru/vtio/article/view/761amiodaronecardiac recipient survivaldrug interactionheart transplantationimmunosuppressive therapy
spellingShingle N. N. Koloskova
V. N. Poptsov
G. M. Salikhova
Amiodarone in cardiac transplant waiting list patients with severe heart failure
Вестник трансплантологии и искусственных органов
amiodarone
cardiac recipient survival
drug interaction
heart transplantation
immunosuppressive therapy
title Amiodarone in cardiac transplant waiting list patients with severe heart failure
title_full Amiodarone in cardiac transplant waiting list patients with severe heart failure
title_fullStr Amiodarone in cardiac transplant waiting list patients with severe heart failure
title_full_unstemmed Amiodarone in cardiac transplant waiting list patients with severe heart failure
title_short Amiodarone in cardiac transplant waiting list patients with severe heart failure
title_sort amiodarone in cardiac transplant waiting list patients with severe heart failure
topic amiodarone
cardiac recipient survival
drug interaction
heart transplantation
immunosuppressive therapy
url https://journal.transpl.ru/vtio/article/view/761
work_keys_str_mv AT nnkoloskova amiodaroneincardiactransplantwaitinglistpatientswithsevereheartfailure
AT vnpoptsov amiodaroneincardiactransplantwaitinglistpatientswithsevereheartfailure
AT gmsalikhova amiodaroneincardiactransplantwaitinglistpatientswithsevereheartfailure