Regulation of innate immune response by miRNAs up-regulated in Stevens-Johnson syndrome with severe ocular complications

Regulation of innate immune response by miRNAs up-regulated in Stevens-Johnson syndrome with severe ocular complications

Abstract Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe mucocutaneous disorders characterized by extensive tissue necrosis; they are often accompanied by severe ocular complications (SOC). The regulatory role of microRNAs (miRNAs) in modulating immune responses in SJS...

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Bibliographic Details
Main Authors: Mayumi Ueta, Hiromi Nishigaki, Hokoru Yoshioka, Shigeru Kinoshita, Chie Sotozono
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Stevens-Johnson syndrome
miRNAs
Plasma
Innate immunity
Severe ocular complications
Online Access:https://doi.org/10.1038/s41598-025-85528-8
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