Evaluation of a Novel PLGA-HA-Based Drug Delivery System Targeting the cell cycle and PI3K/AKT/mTOR Pathway in HCT116 Colorectal Carcinoma Cells with Differing P53 Statuses

Evaluation of a Novel PLGA-HA-Based Drug Delivery System Targeting the cell cycle and PI3K/AKT/mTOR Pathway in HCT116 Colorectal Carcinoma Cells with Differing P53 Statuses

Colorectal carcinoma (CRC) is a very important health problem all over the world, and the P53 gene plays an important role in tumor development and in treatment response. The strategy of developing novel DDS that could target specific tumor pathways is one of the most promising approaches to improv...

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Bibliographic Details
Main Authors: Dlshad H. Hassan, Goran Othman, Esmaeil Babaei
Format: Article
Language:English
Published: Salahaddin University-Erbil 2024-12-01
Series:Zanco Journal of Pure and Applied Sciences
Subjects:
PLGA,
hyaluronic acid
colorectal carcinoma
drug delivery system
PLG PI3K/AKT/mTOR pathway
Online Access:https://zancojournal.su.edu.krd/index.php/JPAS/article/view/2675
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