Hair follicle stem cells and the collapse of self-tolerance in alopecia: the interplay of barrier function, the microbiome, and immunity

The hair follicle is thought to be a site of ‘immune privilege,’ or relative protection from autoimmune and inflammatory responses. In particular, the long-lived, quiescent hair follicle stem cells (HFSCs) are strikingly resistant to cytotoxic immune effectors such as T cells and natural killer (NK)...

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Bibliographic Details
Main Authors: Joseph S Durgin, Sunny Y Wong
Format: Article
Language:English
Published: Springer Nature 2024-11-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.1038/s44321-024-00170-7
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