Preparation and characterization of lactoferrin-polyphenol conjugate with stabilizing effects on fish oil high internal phase Pickering emulsions

The combination of protein and polyphenol is an effective approach to improve the stability of protein emulsions. The lactoferrin (LF)-(−)-epigallocatechin-3-gallate (EGCG) covalent complex (LF-EGCG) was first prepared by alkali-induced reaction, then the structure and physicochemical properties bet...

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Main Authors: Ying Sun, Mantong Zhao, Zhongyuan Liu, Haohao Shi, Xueying Zhang, Yongqiang Zhao, Zhenhua Ma, Gang Yu, Guanghua Xia, Xuanri Shen
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Food Chemistry: X
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590157524007247
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author Ying Sun
Mantong Zhao
Zhongyuan Liu
Haohao Shi
Xueying Zhang
Yongqiang Zhao
Zhenhua Ma
Gang Yu
Guanghua Xia
Xuanri Shen
author_facet Ying Sun
Mantong Zhao
Zhongyuan Liu
Haohao Shi
Xueying Zhang
Yongqiang Zhao
Zhenhua Ma
Gang Yu
Guanghua Xia
Xuanri Shen
author_sort Ying Sun
collection DOAJ
description The combination of protein and polyphenol is an effective approach to improve the stability of protein emulsions. The lactoferrin (LF)-(−)-epigallocatechin-3-gallate (EGCG) covalent complex (LF-EGCG) was first prepared by alkali-induced reaction, then the structure and physicochemical properties between LF-EGCG and non-covalent complex (LF + EGCG) were compared, and finally the stability of complexes to fish oil high internal Pickering emulsions (HIPPEs) was tested. Results showed that LF-EGCG had stronger antioxidant activity, higher thermal stability, and better surface wettability than LF + EGCG. Meanwhile, the complexes showed no cytotoxicity within the tested concentration range (12.5–200 μg/mL). The HIPPEs stabilized with LF-EGCG possessed smaller droplet size, higher ζ-potential, and more uniform oil/water proton distribution. Covalent treatment also enhanced the storage, thermal, freeze-thaw and physical stability of LF HIPPEs. Furthermore, due to the higher antioxidant activity and denser microstructure, LF-EGCG HIPPE can more effectively inhibit the oxidation of fish oil.
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series Food Chemistry: X
spelling doaj-art-6ec74d4ba11b48eb8950314a9a925b552024-12-13T11:01:26ZengElsevierFood Chemistry: X2590-15752024-12-0124101836Preparation and characterization of lactoferrin-polyphenol conjugate with stabilizing effects on fish oil high internal phase Pickering emulsionsYing Sun0Mantong Zhao1Zhongyuan Liu2Haohao Shi3Xueying Zhang4Yongqiang Zhao5Zhenhua Ma6Gang Yu7Guanghua Xia8Xuanri Shen9Hainan Engineering Research Center of Aquatic Resources Efficient Utilization in South China Sea, Key Laboratory of Food Nutrition and Functional Food of Hainan Province, Key Laboratory of Seafood Processing of Haikou, College of Food Science and Technology, Hainan University, Hainan 570228, China.Hainan Engineering Research Center of Aquatic Resources Efficient Utilization in South China Sea, Key Laboratory of Food Nutrition and Functional Food of Hainan Province, Key Laboratory of Seafood Processing of Haikou, College of Food Science and Technology, Hainan University, Hainan 570228, China.Hainan Engineering Research Center of Aquatic Resources Efficient Utilization in South China Sea, Key Laboratory of Food Nutrition and Functional Food of Hainan Province, Key Laboratory of Seafood Processing of Haikou, College of Food Science and Technology, Hainan University, Hainan 570228, China.Hainan Engineering Research Center of Aquatic Resources Efficient Utilization in South China Sea, Key Laboratory of Food Nutrition and Functional Food of Hainan Province, Key Laboratory of Seafood Processing of Haikou, College of Food Science and Technology, Hainan University, Hainan 570228, China.Hainan Engineering Research Center of Aquatic Resources Efficient Utilization in South China Sea, Key Laboratory of Food Nutrition and Functional Food of Hainan Province, Key Laboratory of Seafood Processing of Haikou, College of Food Science and Technology, Hainan University, Hainan 570228, China.Sanya Tropical Fisheries Research Institute, Sanya 572018, ChinaSanya Tropical Fisheries Research Institute, Sanya 572018, ChinaSanya Tropical Fisheries Research Institute, Sanya 572018, ChinaHainan Engineering Research Center of Aquatic Resources Efficient Utilization in South China Sea, Key Laboratory of Food Nutrition and Functional Food of Hainan Province, Key Laboratory of Seafood Processing of Haikou, College of Food Science and Technology, Hainan University, Hainan 570228, China.; Collaborative Innovation Center of Provincial and Ministerial Co-Construction for Marine Food Deep Processing, Dalian Polytechnic University, Dalian 116034, China.; Corresponding author at: Hainan Engineering Research Center of Aquatic Resources Efficient Utilization in South China Sea, Key Laboratory of Food Nutrition and Functional Food of Hainan Province, Key Laboratory of Seafood Processing of Haikou, College of Food Science and Technology, Hainan University, Hainan 570228, China.College of Food Science and Technology, Hainan Tropical Ocean University, Sanya 572022, China.The combination of protein and polyphenol is an effective approach to improve the stability of protein emulsions. The lactoferrin (LF)-(−)-epigallocatechin-3-gallate (EGCG) covalent complex (LF-EGCG) was first prepared by alkali-induced reaction, then the structure and physicochemical properties between LF-EGCG and non-covalent complex (LF + EGCG) were compared, and finally the stability of complexes to fish oil high internal Pickering emulsions (HIPPEs) was tested. Results showed that LF-EGCG had stronger antioxidant activity, higher thermal stability, and better surface wettability than LF + EGCG. Meanwhile, the complexes showed no cytotoxicity within the tested concentration range (12.5–200 μg/mL). The HIPPEs stabilized with LF-EGCG possessed smaller droplet size, higher ζ-potential, and more uniform oil/water proton distribution. Covalent treatment also enhanced the storage, thermal, freeze-thaw and physical stability of LF HIPPEs. Furthermore, due to the higher antioxidant activity and denser microstructure, LF-EGCG HIPPE can more effectively inhibit the oxidation of fish oil.http://www.sciencedirect.com/science/article/pii/S2590157524007247LactoferrinPolyphenolCovalent complexHigh internal phase Pickering emulsionsStability
spellingShingle Ying Sun
Mantong Zhao
Zhongyuan Liu
Haohao Shi
Xueying Zhang
Yongqiang Zhao
Zhenhua Ma
Gang Yu
Guanghua Xia
Xuanri Shen
Preparation and characterization of lactoferrin-polyphenol conjugate with stabilizing effects on fish oil high internal phase Pickering emulsions
Food Chemistry: X
Lactoferrin
Polyphenol
Covalent complex
High internal phase Pickering emulsions
Stability
title Preparation and characterization of lactoferrin-polyphenol conjugate with stabilizing effects on fish oil high internal phase Pickering emulsions
title_full Preparation and characterization of lactoferrin-polyphenol conjugate with stabilizing effects on fish oil high internal phase Pickering emulsions
title_fullStr Preparation and characterization of lactoferrin-polyphenol conjugate with stabilizing effects on fish oil high internal phase Pickering emulsions
title_full_unstemmed Preparation and characterization of lactoferrin-polyphenol conjugate with stabilizing effects on fish oil high internal phase Pickering emulsions
title_short Preparation and characterization of lactoferrin-polyphenol conjugate with stabilizing effects on fish oil high internal phase Pickering emulsions
title_sort preparation and characterization of lactoferrin polyphenol conjugate with stabilizing effects on fish oil high internal phase pickering emulsions
topic Lactoferrin
Polyphenol
Covalent complex
High internal phase Pickering emulsions
Stability
url http://www.sciencedirect.com/science/article/pii/S2590157524007247
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