Growth Kinetics Modeling and Evaluation of Antiphytopathogenic Activity of Newly Isolated Fungicolous <i>Epicoccum nigrum</i> Associated with Dryad’s Saddle (<i>Polyporaceae</i>)

In the present study, an unknown fungal strain was isolated from the fruiting body of a local Dryad’s Saddle mushroom (<i>Polyporaceae</i>). The molecular identification of the isolate was performed by amplification of the ITS1-5.8S-ITS2 region and the strain was identified with 100.00%...

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Main Authors: Radka Baldzhieva, Mariya Brazkova, Denica Blazheva, Bogdan Goranov, Petya Stefanova, Zlatka Ganeva, Desislava Teneva, Petko Denev, Galena Angelova
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Agriculture
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Online Access:https://www.mdpi.com/2077-0472/14/12/2179
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author Radka Baldzhieva
Mariya Brazkova
Denica Blazheva
Bogdan Goranov
Petya Stefanova
Zlatka Ganeva
Desislava Teneva
Petko Denev
Galena Angelova
author_facet Radka Baldzhieva
Mariya Brazkova
Denica Blazheva
Bogdan Goranov
Petya Stefanova
Zlatka Ganeva
Desislava Teneva
Petko Denev
Galena Angelova
author_sort Radka Baldzhieva
collection DOAJ
description In the present study, an unknown fungal strain was isolated from the fruiting body of a local Dryad’s Saddle mushroom (<i>Polyporaceae</i>). The molecular identification of the isolate was performed by amplification of the ITS1-5.8S-ITS2 region and the strain was identified with 100.00% confidence as <i>Epicoccum nigrum</i>. The morphological characteristics, including the distinctive colony pigmentation, conidiophore structure, and conidial shape, were determined to ensure comprehensive characterization of the fungus. The modeling of the kinetics of the growth process was conducted with the applying the logistic curve model and the reverse autocatalytic growth model, and the concentrations of the compounds in the nutrient medium required for the <i>E. nigrum</i> development were established. Controlled submerged cultivation was carried out for cultural liquid obtaining, which was further used for the evaluation of the biological activities. The untreated cultural liquid demonstrated antimicrobial activity against <i>Sclerotinia sclerotiorum</i> where the minimal inhibitory concentration was 1.25 mg/mL. Antimicrobial activity was also detected toward <i>Botrytis cinerea</i> (2.5 mg/mL) and <i>Aspergillus flavus</i> (2.5 mg/mL). The direct utilization of crude cultural liquid for phytopathogenic control is a sustainable approach that will provide the opportunity for the development of an environmentally friendly manufacturing process.
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spelling doaj-art-6eb58cfd0e8a431581076809e15b1d5a2024-12-27T14:02:56ZengMDPI AGAgriculture2077-04722024-11-011412217910.3390/agriculture14122179Growth Kinetics Modeling and Evaluation of Antiphytopathogenic Activity of Newly Isolated Fungicolous <i>Epicoccum nigrum</i> Associated with Dryad’s Saddle (<i>Polyporaceae</i>)Radka Baldzhieva0Mariya Brazkova1Denica Blazheva2Bogdan Goranov3Petya Stefanova4Zlatka Ganeva5Desislava Teneva6Petko Denev7Galena Angelova8Department of Microbiology and Biotechnology, University of Food Technologies, 26 Maritsa Blvd., 4002 Plovdiv, BulgariaDepartment of Microbiology and Biotechnology, University of Food Technologies, 26 Maritsa Blvd., 4002 Plovdiv, BulgariaDepartment of Microbiology and Biotechnology, University of Food Technologies, 26 Maritsa Blvd., 4002 Plovdiv, BulgariaDepartment of Microbiology and Biotechnology, University of Food Technologies, 26 Maritsa Blvd., 4002 Plovdiv, BulgariaDepartment of Microbiology and Biotechnology, University of Food Technologies, 26 Maritsa Blvd., 4002 Plovdiv, BulgariaDepartment of Microbiology and Biotechnology, University of Food Technologies, 26 Maritsa Blvd., 4002 Plovdiv, BulgariaLaboratory of Biologically Active Substances, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 139 Ruski Blvd., 4000 Plovdiv, BulgariaLaboratory of Biologically Active Substances, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 139 Ruski Blvd., 4000 Plovdiv, BulgariaDepartment of Microbiology and Biotechnology, University of Food Technologies, 26 Maritsa Blvd., 4002 Plovdiv, BulgariaIn the present study, an unknown fungal strain was isolated from the fruiting body of a local Dryad’s Saddle mushroom (<i>Polyporaceae</i>). The molecular identification of the isolate was performed by amplification of the ITS1-5.8S-ITS2 region and the strain was identified with 100.00% confidence as <i>Epicoccum nigrum</i>. The morphological characteristics, including the distinctive colony pigmentation, conidiophore structure, and conidial shape, were determined to ensure comprehensive characterization of the fungus. The modeling of the kinetics of the growth process was conducted with the applying the logistic curve model and the reverse autocatalytic growth model, and the concentrations of the compounds in the nutrient medium required for the <i>E. nigrum</i> development were established. Controlled submerged cultivation was carried out for cultural liquid obtaining, which was further used for the evaluation of the biological activities. The untreated cultural liquid demonstrated antimicrobial activity against <i>Sclerotinia sclerotiorum</i> where the minimal inhibitory concentration was 1.25 mg/mL. Antimicrobial activity was also detected toward <i>Botrytis cinerea</i> (2.5 mg/mL) and <i>Aspergillus flavus</i> (2.5 mg/mL). The direct utilization of crude cultural liquid for phytopathogenic control is a sustainable approach that will provide the opportunity for the development of an environmentally friendly manufacturing process.https://www.mdpi.com/2077-0472/14/12/2179<i>Epicoccum nigrum</i><i>Polyporaceae</i>fungicolouskinetics modelingantiphytopathogenic activity
spellingShingle Radka Baldzhieva
Mariya Brazkova
Denica Blazheva
Bogdan Goranov
Petya Stefanova
Zlatka Ganeva
Desislava Teneva
Petko Denev
Galena Angelova
Growth Kinetics Modeling and Evaluation of Antiphytopathogenic Activity of Newly Isolated Fungicolous <i>Epicoccum nigrum</i> Associated with Dryad’s Saddle (<i>Polyporaceae</i>)
Agriculture
<i>Epicoccum nigrum</i>
<i>Polyporaceae</i>
fungicolous
kinetics modeling
antiphytopathogenic activity
title Growth Kinetics Modeling and Evaluation of Antiphytopathogenic Activity of Newly Isolated Fungicolous <i>Epicoccum nigrum</i> Associated with Dryad’s Saddle (<i>Polyporaceae</i>)
title_full Growth Kinetics Modeling and Evaluation of Antiphytopathogenic Activity of Newly Isolated Fungicolous <i>Epicoccum nigrum</i> Associated with Dryad’s Saddle (<i>Polyporaceae</i>)
title_fullStr Growth Kinetics Modeling and Evaluation of Antiphytopathogenic Activity of Newly Isolated Fungicolous <i>Epicoccum nigrum</i> Associated with Dryad’s Saddle (<i>Polyporaceae</i>)
title_full_unstemmed Growth Kinetics Modeling and Evaluation of Antiphytopathogenic Activity of Newly Isolated Fungicolous <i>Epicoccum nigrum</i> Associated with Dryad’s Saddle (<i>Polyporaceae</i>)
title_short Growth Kinetics Modeling and Evaluation of Antiphytopathogenic Activity of Newly Isolated Fungicolous <i>Epicoccum nigrum</i> Associated with Dryad’s Saddle (<i>Polyporaceae</i>)
title_sort growth kinetics modeling and evaluation of antiphytopathogenic activity of newly isolated fungicolous i epicoccum nigrum i associated with dryad s saddle i polyporaceae i
topic <i>Epicoccum nigrum</i>
<i>Polyporaceae</i>
fungicolous
kinetics modeling
antiphytopathogenic activity
url https://www.mdpi.com/2077-0472/14/12/2179
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