ANXA4 restricts HBV replication by inhibiting autophagic degradation of MCM2 in chronic hepatitis B

ANXA4 restricts HBV replication by inhibiting autophagic degradation of MCM2 in chronic hepatitis B

Abstract Background Hepatitis B virus (HBV) is an enveloped DNA virus that causes chronic hepatitis B (CHB) infection. Annexin, a Ca2+-activated protein, is widely expressed in various organs and tissues and has potential utility in disease diagnosis and treatment. However, the relationship between...

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Bibliographic Details
Main Authors:	Luo Yang, Xianzhi Liu, Limin Zhen, Ying Liu, Lina Wu, Wenxiong Xu, Liang Peng, Chan Xie
Format:	Article
Language:	English
Published:	BMC 2024-11-01
Series:	BMC Medicine
Subjects:	Chronic hepatitis B (CHB) Annexin A4 (ANXA4) Autophagy Minichromosome maintenance complex component 2 (MCM2) HBV replication
Online Access:	https://doi.org/10.1186/s12916-024-03724-1
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