In Vivo Bioluminescence Imaging Validation of a Human Biopsy–Derived Orthotopic Mouse Model of Glioblastoma Multiforme

In Vivo Bioluminescence Imaging Validation of a Human Biopsy–Derived Orthotopic Mouse Model of Glioblastoma Multiforme

Glioblastoma multiforme (GBM), the most aggressive brain malignancy, is characterized by extensive cellular proliferation, angiogenesis, and single-cell infiltration into the brain. We have previously shown that a xenograft model based on serial xenotransplantation of human biopsy spheroids in immun...

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Bibliographic Details
Main Authors: Monika A. Jarzabek, Peter C. Huszthy, Kai O. Skaftnesmo, Emmet McCormack, Patrick Dicker, Jochen H.M. Prehn, Rolf Bjerkvig, Annette T. Byrne
Format: Article
Language:English
Published: SAGE Publishing 2013-05-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2012.00029
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