Dexmedetomidine Improves Learning Functions in Male Rats Modeling Cognitive Impairment by Modulating the BDNF/TrkB/CREB Signaling Pathway
Dexmedetomidine (DEX) is a selective alpha-2 adrenergic receptor agonist with sedative and anxiolytic properties. Increasing evidence reports that DEX has a neuroprotective effect. In this study, we investigated the potential effects of DEX on learning and memory functions in rats with experimental...
Saved in:
| Main Authors: | Sinan Saral, Tolga Mercantepe, Atilla Topçu, Ali Koray Kaya, Aykut Öztürk |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-12-01
|
| Series: | Life |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-1729/14/12/1672 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Morinda officinalis oligosaccharides alleviate chronic unpredictable mild stress-induced depression through the BDNF/TrkB/CREB pathway and symptoms of sexual dysfunction in mice
by: Mengjie He, et al.
Published: (2025-01-01) -
Activation of BDNF–TrkB Signaling in Specific Structures of the Sheep Brain by Kynurenic Acid
by: Katarzyna Roszkowicz-Ostrowska, et al.
Published: (2024-11-01) -
Exercise-conditioned plasma ameliorates postoperative cognitive dysfunction by activating hippocampal cholinergic circuit and enhancing BDNF/TrkB signaling
by: Xiaodi Lu, et al.
Published: (2024-11-01) -
Functional Remediation Improves Serum BDNF and TrkB Levels in Euthymic Patients with Bipolar Disorder: A Randomized Trial Study
by: Li R, et al.
Published: (2025-01-01) -
GATA1-mediated macrophage polarization via TrkB/cGMP–PKG signaling pathway to promote the development of preeclampsia
by: Wushan Li, et al.
Published: (2025-01-01)