Clinical and Laboratory Profile of People Afflicted with Melioidosis: A Retrospective Study
Aim: Melioidosis, caused by Burkholderia pseudomallei, is an important disease in some parts of the developing countries and is now categorized as an emerging infection and a global threat. The present study was carried out to ascertain the alterations on the hematological, hepatic, and renal parame...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Indian Journal of Medical Specialities |
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| Online Access: | https://journals.lww.com/10.4103/INJMS.INJMS_45_19 |
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| author | Ponmaleri Koroth Swapna Ramakrishna Pai Jakribettu Thomas George Ponmaleri Koroth Manoj Kumar Manjeshwar Srinath Baliga |
| author_facet | Ponmaleri Koroth Swapna Ramakrishna Pai Jakribettu Thomas George Ponmaleri Koroth Manoj Kumar Manjeshwar Srinath Baliga |
| author_sort | Ponmaleri Koroth Swapna |
| collection | DOAJ |
| description | Aim:
Melioidosis, caused by Burkholderia pseudomallei, is an important disease in some parts of the developing countries and is now categorized as an emerging infection and a global threat. The present study was carried out to ascertain the alterations on the hematological, hepatic, and renal parameters in the infected people.
Materials and Methods:
This was a retrospective study and was conducted in a tertiary care hospital in India. Data were analyzed in people who were diagnosed to be infected by B. pseudomallei during January 2010–December 2016. A total of 28 people were included in the study and compared with healthy individuals who were tested negative for any infectious and chronic diseases.
Results:
The results indicated that the infection caused diverse clinical manifestations such as fever, cough, dyspnea, joint pain, headache, bodyache, weight loss, swelling, and decrease in appetite. There was significant difference in the various hematological and hepatic endpoints, while there was no such difference in the renal function test parameters.
Conclusions:
For the first time, this study indicates that acute infection with melioidosis causes alterations in hematological and hepatic parameters in people with melioidosis. |
| format | Article |
| id | doaj-art-6e9e6af4d93b48b5a054005fec676bf2 |
| institution | Kabale University |
| issn | 0976-2884 0976-2892 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Medical Specialities |
| spelling | doaj-art-6e9e6af4d93b48b5a054005fec676bf22025-08-25T08:32:52ZengWolters Kluwer Medknow PublicationsIndian Journal of Medical Specialities0976-28840976-28922020-01-01111101410.4103/INJMS.INJMS_45_19Clinical and Laboratory Profile of People Afflicted with Melioidosis: A Retrospective StudyPonmaleri Koroth SwapnaRamakrishna Pai JakribettuThomas GeorgePonmaleri Koroth Manoj KumarManjeshwar Srinath BaligaAim: Melioidosis, caused by Burkholderia pseudomallei, is an important disease in some parts of the developing countries and is now categorized as an emerging infection and a global threat. The present study was carried out to ascertain the alterations on the hematological, hepatic, and renal parameters in the infected people. Materials and Methods: This was a retrospective study and was conducted in a tertiary care hospital in India. Data were analyzed in people who were diagnosed to be infected by B. pseudomallei during January 2010–December 2016. A total of 28 people were included in the study and compared with healthy individuals who were tested negative for any infectious and chronic diseases. Results: The results indicated that the infection caused diverse clinical manifestations such as fever, cough, dyspnea, joint pain, headache, bodyache, weight loss, swelling, and decrease in appetite. There was significant difference in the various hematological and hepatic endpoints, while there was no such difference in the renal function test parameters. Conclusions: For the first time, this study indicates that acute infection with melioidosis causes alterations in hematological and hepatic parameters in people with melioidosis.https://journals.lww.com/10.4103/INJMS.INJMS_45_19burkholderia pseudomalleiclinicalhematologicalhepaticmelioidosisrenal |
| spellingShingle | Ponmaleri Koroth Swapna Ramakrishna Pai Jakribettu Thomas George Ponmaleri Koroth Manoj Kumar Manjeshwar Srinath Baliga Clinical and Laboratory Profile of People Afflicted with Melioidosis: A Retrospective Study Indian Journal of Medical Specialities burkholderia pseudomallei clinical hematological hepatic melioidosis renal |
| title | Clinical and Laboratory Profile of People Afflicted with Melioidosis: A Retrospective Study |
| title_full | Clinical and Laboratory Profile of People Afflicted with Melioidosis: A Retrospective Study |
| title_fullStr | Clinical and Laboratory Profile of People Afflicted with Melioidosis: A Retrospective Study |
| title_full_unstemmed | Clinical and Laboratory Profile of People Afflicted with Melioidosis: A Retrospective Study |
| title_short | Clinical and Laboratory Profile of People Afflicted with Melioidosis: A Retrospective Study |
| title_sort | clinical and laboratory profile of people afflicted with melioidosis a retrospective study |
| topic | burkholderia pseudomallei clinical hematological hepatic melioidosis renal |
| url | https://journals.lww.com/10.4103/INJMS.INJMS_45_19 |
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