Protective role for properdin in progression of experimental murine atherosclerosis.

Protective role for properdin in progression of experimental murine atherosclerosis.

Genetic, dietary and immune factors contribute to the pathogenesis of atherosclerosis in humans and mice. Complement activation is an integral part of the innate immune defence but also shapes cellular responses and influences directly triglyceride synthesis. Deficiency of Factor B of the alternativ...

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Bibliographic Details
Main Authors: Tanja Steiner, Lorenza Francescut, Simon Byrne, Timothy Hughes, Archana Jayanthi, Irina Guschina, John Harwood, Katherine Cianflone, Cordula Stover, Sheila Francis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0092404&type=printable
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