Interleukin-17 signaling influences CD8+ T cell immunity and tumor progression according to the IL-17 receptor subunit expression pattern in cancer cells

Interleukin-17 signaling influences CD8+ T cell immunity and tumor progression according to the IL-17 receptor subunit expression pattern in cancer cells

IL-17 immune responses in cancer are controversial, with both tumor-promoting and tumor-repressing effects observed. To clarify the role of IL-17 signaling in cancer progression, we used syngeneic tumor models from different tissue origins. We found that deficiencies in host IL-17RA or IL-17A/F expr...

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Bibliographic Details
Main Authors: Constanza Rodriguez, Cintia L. Araujo Furlan, Jimena Tosello Boari, Sabrina N. Bossio, Santiago Boccardo, Laura Fozzatti, Fernando P. Canale, Cristian G. Beccaria, Nicolás G. Nuñez, Danilo G. Ceschin, Eliane Piaggio, Adriana Gruppi, Carolina L. Montes, Eva V. Acosta Rodríguez
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:OncoImmunology
Subjects:
Angiogenesis
CD8+ lymphocytes
IL-17RC
inflammation
interleukin 17 (IL-17)
tumor immunology
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2023.2261326
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https://www.tandfonline.com/doi/10.1080/2162402X.2023.2261326

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