KLF2 controls the apoptosis of neutrophils and is associated with disease activity of systemic lupus erythematosus

KLF2 controls the apoptosis of neutrophils and is associated with disease activity of systemic lupus erythematosus

Abstract Background Neutropenia is more common in patients with systemic lupus erythematosus (SLE) and is a major cause of life-threatening infections. The increased apoptosis of neutrophils is likely to be an essential cause of neutropenia in SLE. However, the detailed mechanisms of increased neutr...

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Bibliographic Details
Main Authors: Hongshuai Zhao, Zaichuan Lin, Peiwen Zhang, Jiayue Rao, Shumin Xu, Qing Luo, Junming Li
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Arthritis Research & Therapy
Subjects:
Systemic lupus erythematosus
Krüppel-like factor 2
Neutrophil
Apoptosis
SLE disease activity index
Online Access:https://doi.org/10.1186/s13075-024-03461-z
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