Missed Opportunities for Early De-Escalation of Antipseudomonal Beta-Lactam Antimicrobial Therapy in Enterobacterales Bloodstream Infection

Missed Opportunities for Early De-Escalation of Antipseudomonal Beta-Lactam Antimicrobial Therapy in Enterobacterales Bloodstream Infection

<b>Background:</b> Antipseudomonal β-lactams (APBL) are commonly used for empirical therapy of Gram-negative bloodstream infections (BSI). This retrospective cohort study examines risk factors for prolonged APBL use (≥48 h) in patients with Enterobacterales BSI and compares 28-day mortal...

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Bibliographic Details
Main Authors: Mollie Reese, P. Brandon Bookstaver, Joseph Kohn, Casey Troficanto, Emily Yongue, Hana R. Winders, Majdi N. Al-Hasan
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Antibiotics
Subjects:
bacteremia
antibiotics
gram-negative
sepsis
empirical therapy
outcome
Online Access:https://www.mdpi.com/2079-6382/13/11/1031
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