Network-based approach identifies key genes associated with tumor heterogeneity in HPV positive and negative head and neck cancer patients

Network-based approach identifies key genes associated with tumor heterogeneity in HPV positive and negative head and neck cancer patients

Abstract Head and Neck Squamous Cell Carcinoma (HNSCC) is the seventh most prevalent cancer worldwide and is classified as human papillomavirus (HPV) positive or negative. Substantial heterogeneity has been observed in the two groups, posing a significant clinical challenge. In the disease context,...

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Bibliographic Details
Main Authors: Sumeet Patiyal, Piyush Agrawal
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Network-based approach
Head and neck cancer
Human papilloma virus
Tumor heterogeneity
Differentially expressed genes
Cancer hallmarks
Online Access:https://doi.org/10.1038/s41598-025-13604-0
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