Predictors of Nasal Continuous Positive Airway Pressure Failure in Preterm Infants With Respiratory Distress Syndrome
Respiratory support in infants with respiratory distress syndrome (RDS) plays an important role in the reduction of mortality and complications, but the treatment fails in some infants. This study aimed to identify the predictors of continuous positive airway pressure (CPAP) failure in preterm infa...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2024-10-01
|
| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/11227 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846137807514370048 |
|---|---|
| author | Rozhin Hesami Mohammad Kazem Sabzehei Behnaz Basiri Maryam Shokouhi Solgi Nasrin Jiryaee |
| author_facet | Rozhin Hesami Mohammad Kazem Sabzehei Behnaz Basiri Maryam Shokouhi Solgi Nasrin Jiryaee |
| author_sort | Rozhin Hesami |
| collection | DOAJ |
| description |
Respiratory support in infants with respiratory distress syndrome (RDS) plays an important role in the reduction of mortality and complications, but the treatment fails in some infants. This study aimed to identify the predictors of continuous positive airway pressure (CPAP) failure in preterm infants with RDS. This cross-sectional retrospective study was conducted on RDS-diagnosed preterm infants admitted to the neonatal intensive care unit of Fatemieh Hospital (Hamadan city) in 2021-2022. The infants were examined in terms of risk factors for CPAP failure. Data extracted from the medical records were recorded in a checklist and analyzed with SPSS version 21 software at a confidence level of 95%. CPAP failure was recorded in 37.6% of the studied 202 infants. The need for resuscitation at birth, low gestational age, low birth weight, multiple births, low 1-min and 5-min Apgar scores, the need for higher FIO2 and PEEP, acidosis, and the need for surfactant administration were significantly associated with CPAP failure. In logistic regression, low gestational age (OR 1.30, 95% CI: 1.082-1.576) and the need for resuscitation at birth (OR 0.426, 95% CI: 0.202-0.898) were the major predictors of CPAP failure. Lower gestational age and the need for PPV in the delivery room are good predictors of CPAP failure in preterm infants with RDS, who receive nasal CPAP as primary respiratory support.
|
| format | Article |
| id | doaj-art-6d9c8b1c14bf4121959f694bde1b56fa |
| institution | Kabale University |
| issn | 0044-6025 1735-9694 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj-art-6d9c8b1c14bf4121959f694bde1b56fa2024-12-08T04:32:04ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942024-10-0162110.18502/acta.v62i1.16884Predictors of Nasal Continuous Positive Airway Pressure Failure in Preterm Infants With Respiratory Distress SyndromeRozhin Hesami0Mohammad Kazem Sabzehei1Behnaz Basiri2Maryam Shokouhi Solgi3Nasrin Jiryaee4School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.Department of Pediatrics, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.Department of Pediatrics, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.Department of Pediatrics, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.Department of Biostatistics, School of Health, Hamadan University of Medical Sciences, Hamadan, Iran. Respiratory support in infants with respiratory distress syndrome (RDS) plays an important role in the reduction of mortality and complications, but the treatment fails in some infants. This study aimed to identify the predictors of continuous positive airway pressure (CPAP) failure in preterm infants with RDS. This cross-sectional retrospective study was conducted on RDS-diagnosed preterm infants admitted to the neonatal intensive care unit of Fatemieh Hospital (Hamadan city) in 2021-2022. The infants were examined in terms of risk factors for CPAP failure. Data extracted from the medical records were recorded in a checklist and analyzed with SPSS version 21 software at a confidence level of 95%. CPAP failure was recorded in 37.6% of the studied 202 infants. The need for resuscitation at birth, low gestational age, low birth weight, multiple births, low 1-min and 5-min Apgar scores, the need for higher FIO2 and PEEP, acidosis, and the need for surfactant administration were significantly associated with CPAP failure. In logistic regression, low gestational age (OR 1.30, 95% CI: 1.082-1.576) and the need for resuscitation at birth (OR 0.426, 95% CI: 0.202-0.898) were the major predictors of CPAP failure. Lower gestational age and the need for PPV in the delivery room are good predictors of CPAP failure in preterm infants with RDS, who receive nasal CPAP as primary respiratory support. https://acta.tums.ac.ir/index.php/acta/article/view/11227Preterm infantsRespiratory distress syndromContinuous positive airway pressure |
| spellingShingle | Rozhin Hesami Mohammad Kazem Sabzehei Behnaz Basiri Maryam Shokouhi Solgi Nasrin Jiryaee Predictors of Nasal Continuous Positive Airway Pressure Failure in Preterm Infants With Respiratory Distress Syndrome Acta Medica Iranica Preterm infants Respiratory distress syndrom Continuous positive airway pressure |
| title | Predictors of Nasal Continuous Positive Airway Pressure Failure in Preterm Infants With Respiratory Distress Syndrome |
| title_full | Predictors of Nasal Continuous Positive Airway Pressure Failure in Preterm Infants With Respiratory Distress Syndrome |
| title_fullStr | Predictors of Nasal Continuous Positive Airway Pressure Failure in Preterm Infants With Respiratory Distress Syndrome |
| title_full_unstemmed | Predictors of Nasal Continuous Positive Airway Pressure Failure in Preterm Infants With Respiratory Distress Syndrome |
| title_short | Predictors of Nasal Continuous Positive Airway Pressure Failure in Preterm Infants With Respiratory Distress Syndrome |
| title_sort | predictors of nasal continuous positive airway pressure failure in preterm infants with respiratory distress syndrome |
| topic | Preterm infants Respiratory distress syndrom Continuous positive airway pressure |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/11227 |
| work_keys_str_mv | AT rozhinhesami predictorsofnasalcontinuouspositiveairwaypressurefailureinpreterminfantswithrespiratorydistresssyndrome AT mohammadkazemsabzehei predictorsofnasalcontinuouspositiveairwaypressurefailureinpreterminfantswithrespiratorydistresssyndrome AT behnazbasiri predictorsofnasalcontinuouspositiveairwaypressurefailureinpreterminfantswithrespiratorydistresssyndrome AT maryamshokouhisolgi predictorsofnasalcontinuouspositiveairwaypressurefailureinpreterminfantswithrespiratorydistresssyndrome AT nasrinjiryaee predictorsofnasalcontinuouspositiveairwaypressurefailureinpreterminfantswithrespiratorydistresssyndrome |