Guanidine aptamers are present in vertebrate RNAs associated with calcium signaling and neuromuscular function
Abstract Guanidine is a protein denaturant that is a widely used constituent in explosives, plastics, and resins. Its effects on muscle contraction were initially reported in 1876, which eventually led to the use of guanidine as a treatment for certain ataxia symptoms such as those caused by Lambert...
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| Main Authors: | Kumari Kavita, Aya Narunsky, Jessica J. Mohsen, Isha Mahadeshwar, Michael G. Mohsen, Yu-Shin Chang, Ronald R. Breaker |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-62815-6 |
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