Sulforaphane attenuates dextran sodium sulphate induced intestinal inflammation via IL-10/STAT3 signaling mediated macrophage phenotype switching

Sulforaphane attenuates dextran sodium sulphate induced intestinal inflammation via IL-10/STAT3 signaling mediated macrophage phenotype switching

Innate immunity, particularly macrophages, is critical for intestinal homeostasis. Sulforaphane, a dietary isothiocyanate from cruciferous vegetables, has been reported to protect against intestinal inflammation. However, the role of macrophages in sulforaphane mediated intestinal inflammation and t...

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Bibliographic Details
Main Authors: Yuyang Sun, Jiqing Tang, Cui Li, Jun Liu, Haijie Liu
Format: Article
Language:English
Published: Tsinghua University Press 2022-01-01
Series:Food Science and Human Wellness
Subjects:
BMDMs
Intestinal inflammation
IL-10
Macrophage phenotype
STAT3
Sulforaphane
Online Access:http://www.sciencedirect.com/science/article/pii/S221345302100080X
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