Comprehensive analysis of plasma methylome reveals distinct patterns of methylation changes between responders and non-responders to neoadjuvant chemotherapy in breast cancer

Comprehensive analysis of plasma methylome reveals distinct patterns of methylation changes between responders and non-responders to neoadjuvant chemotherapy in breast cancer

The potential of cell-free DNA (cfDNA) methylation profiling in oncology is increasingly recognized for its ability to offer a comprehensive assessment of tumor biology. In this report, we explore the plasma methylome dynamics in patients with early breast cancer (BC) undergoing neoadjuvant chemothe...

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Bibliographic Details
Main Authors: Francesco Ravera, Martina Dameri, Pier Vitale Nuzzo, Mario Stabile, Piero Fregatti, Alberto Ballestrero, Lorenzo Ferrando, Gabriele Zoppoli
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:The Journal of Liquid Biopsy
Subjects:
Breast cancer
Cell-free DNA
DNA methylation
Neoadjuvant chemotherapy
Response to therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2950195424000249
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