Modifiable risk factors for hypertensive disorders in pregnancy

Hypertensive disorders in pregnancy (HDPs) are the leading causes of maternal mortality and morbidity. This study explored whether micronutrient intake and psychological distress were associated with HDPs. Micronutrients include folate and vitamin B12. Psychological distress refers to perceived stre...

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Main Authors: Mei-Wei Chang, Alai Tan, Joshua M. Smyth, Duane T. Wegener
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Critical Public Health
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Online Access:https://www.tandfonline.com/doi/10.1080/09581596.2025.2480277
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author Mei-Wei Chang
Alai Tan
Joshua M. Smyth
Duane T. Wegener
author_facet Mei-Wei Chang
Alai Tan
Joshua M. Smyth
Duane T. Wegener
author_sort Mei-Wei Chang
collection DOAJ
description Hypertensive disorders in pregnancy (HDPs) are the leading causes of maternal mortality and morbidity. This study explored whether micronutrient intake and psychological distress were associated with HDPs. Micronutrients include folate and vitamin B12. Psychological distress refers to perceived stress, prenatal distress, and prenatal depression. HDPs were defined as systolic blood pressure (BP) ≥130 mmHg or diastolic BP ≥80 mmHg. Data were collected at ≤17 weeks gestation (T1), 25–27 weeks gestation (T2), and 35–37 weeks gestation (T3). T-tests comparing those with and without HDP were performed to explore the associations. Results showed that folate and vitamin B12 were associated with HDPs at T1 and T2 (T1: d = –0.41, d = –0.52; T2: d = –0.43, d = –0.24). Psychological distress was positively associated with HDPs, but associations varied between timepoints and by measure – prenatal distress at all times (T1: d = 0.26; T2: d = 0.54, T3: d = 0.40), perceived stress at T3 (d = 0.34), and prenatal depression at T2 and T3 (T2, d = 0.47; T3: d = 0.68). In summary, micronutrient intake and psychological distress are associated with HDPs but varied by construct and across gestational age.
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spelling doaj-art-6d3e7b9bca8646a5a7d6abe3b7e51bca2025-08-20T03:42:37ZengTaylor & Francis GroupCritical Public Health0958-15961469-36822025-12-0135110.1080/09581596.2025.2480277Modifiable risk factors for hypertensive disorders in pregnancyMei-Wei Chang0Alai Tan1Joshua M. Smyth2Duane T. Wegener3College of Nursing, The Ohio State University, Columbus, OH, USACollege of Nursing, The Ohio State University, Columbus, OH, USADepartment of Psychology, The Ohio State University, Columbus, OH, USADepartment of Psychology, The Ohio State University, Columbus, OH, USAHypertensive disorders in pregnancy (HDPs) are the leading causes of maternal mortality and morbidity. This study explored whether micronutrient intake and psychological distress were associated with HDPs. Micronutrients include folate and vitamin B12. Psychological distress refers to perceived stress, prenatal distress, and prenatal depression. HDPs were defined as systolic blood pressure (BP) ≥130 mmHg or diastolic BP ≥80 mmHg. Data were collected at ≤17 weeks gestation (T1), 25–27 weeks gestation (T2), and 35–37 weeks gestation (T3). T-tests comparing those with and without HDP were performed to explore the associations. Results showed that folate and vitamin B12 were associated with HDPs at T1 and T2 (T1: d = –0.41, d = –0.52; T2: d = –0.43, d = –0.24). Psychological distress was positively associated with HDPs, but associations varied between timepoints and by measure – prenatal distress at all times (T1: d = 0.26; T2: d = 0.54, T3: d = 0.40), perceived stress at T3 (d = 0.34), and prenatal depression at T2 and T3 (T2, d = 0.47; T3: d = 0.68). In summary, micronutrient intake and psychological distress are associated with HDPs but varied by construct and across gestational age.https://www.tandfonline.com/doi/10.1080/09581596.2025.2480277Folatevitamin B12stressprenatal distressprenatal depression
spellingShingle Mei-Wei Chang
Alai Tan
Joshua M. Smyth
Duane T. Wegener
Modifiable risk factors for hypertensive disorders in pregnancy
Critical Public Health
Folate
vitamin B12
stress
prenatal distress
prenatal depression
title Modifiable risk factors for hypertensive disorders in pregnancy
title_full Modifiable risk factors for hypertensive disorders in pregnancy
title_fullStr Modifiable risk factors for hypertensive disorders in pregnancy
title_full_unstemmed Modifiable risk factors for hypertensive disorders in pregnancy
title_short Modifiable risk factors for hypertensive disorders in pregnancy
title_sort modifiable risk factors for hypertensive disorders in pregnancy
topic Folate
vitamin B12
stress
prenatal distress
prenatal depression
url https://www.tandfonline.com/doi/10.1080/09581596.2025.2480277
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AT duanetwegener modifiableriskfactorsforhypertensivedisordersinpregnancy