Acrylamide exposure: Dietary risks of oral carcinoma in non-smokers
Acrylamide, classified as a probable human carcinogen, is primarily found in plant-derived foods like potatoes, grains, and coffee, with heightened formation during high-temperature cooking. Exposure occurs through food and cigarette smoke. Rodent studies indicate an increased cancer risk, with acry...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-06-01
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| Series: | Oral Oncology Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772906024002012 |
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| author | Gokul Sudhakaran Kuppusamy Sathishkumar Meivelu Moovendhan |
| author_facet | Gokul Sudhakaran Kuppusamy Sathishkumar Meivelu Moovendhan |
| author_sort | Gokul Sudhakaran |
| collection | DOAJ |
| description | Acrylamide, classified as a probable human carcinogen, is primarily found in plant-derived foods like potatoes, grains, and coffee, with heightened formation during high-temperature cooking. Exposure occurs through food and cigarette smoke. Rodent studies indicate an increased cancer risk, with acrylamide converting into glycidamide, causing DNA damage. Its hydrophilic nature allows penetration into various body tissues. Though evidence linking dietary acrylamide intake to head and neck cancer risk is inconclusive, potential exceptions exist. Further research, particularly on non-smokers, is recommended. Minimizing exposure via dietary and cooking modifications is crucial. Additional studies on human acrylamide and oral cancer risk are needed for effective public health strategies. |
| format | Article |
| id | doaj-art-6c814477e90c48e7a887ae336135f7b4 |
| institution | Kabale University |
| issn | 2772-9060 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Oral Oncology Reports |
| spelling | doaj-art-6c814477e90c48e7a887ae336135f7b42025-01-09T06:15:55ZengElsevierOral Oncology Reports2772-90602024-06-0110100355Acrylamide exposure: Dietary risks of oral carcinoma in non-smokersGokul Sudhakaran0Kuppusamy Sathishkumar1Meivelu Moovendhan2Corresponding author. Center for Global Health Research Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences Kancheepuram district, Tamil Nadu, India.; Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Tamil Nadu, IndiaCenter for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Tamil Nadu, IndiaCenter for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Tamil Nadu, IndiaAcrylamide, classified as a probable human carcinogen, is primarily found in plant-derived foods like potatoes, grains, and coffee, with heightened formation during high-temperature cooking. Exposure occurs through food and cigarette smoke. Rodent studies indicate an increased cancer risk, with acrylamide converting into glycidamide, causing DNA damage. Its hydrophilic nature allows penetration into various body tissues. Though evidence linking dietary acrylamide intake to head and neck cancer risk is inconclusive, potential exceptions exist. Further research, particularly on non-smokers, is recommended. Minimizing exposure via dietary and cooking modifications is crucial. Additional studies on human acrylamide and oral cancer risk are needed for effective public health strategies.http://www.sciencedirect.com/science/article/pii/S2772906024002012AcrylamideCancerDietSmoking |
| spellingShingle | Gokul Sudhakaran Kuppusamy Sathishkumar Meivelu Moovendhan Acrylamide exposure: Dietary risks of oral carcinoma in non-smokers Oral Oncology Reports Acrylamide Cancer Diet Smoking |
| title | Acrylamide exposure: Dietary risks of oral carcinoma in non-smokers |
| title_full | Acrylamide exposure: Dietary risks of oral carcinoma in non-smokers |
| title_fullStr | Acrylamide exposure: Dietary risks of oral carcinoma in non-smokers |
| title_full_unstemmed | Acrylamide exposure: Dietary risks of oral carcinoma in non-smokers |
| title_short | Acrylamide exposure: Dietary risks of oral carcinoma in non-smokers |
| title_sort | acrylamide exposure dietary risks of oral carcinoma in non smokers |
| topic | Acrylamide Cancer Diet Smoking |
| url | http://www.sciencedirect.com/science/article/pii/S2772906024002012 |
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