The Role of Shear Wave Elastography in Predicting Early Stage Liver Fibrosis
Aim: We examined the relationship between shear wave elastography (SWE) values and histopathological results in our study. Thus, we found the sensitivity of SWE in demonstrating early fibrosis. Materials and Methods: A total of consecutive 70 patients with chronic hepatitis B were prospectively eval...
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Selcuk University Press
2024-02-01
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| Series: | Genel Tıp Dergisi |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/3349189 |
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| author | Fatma Zeynep Arslan Mehmet Karagülle Abdullah Soydan Mahmutoğlu Mehmet Semih Çakır Ayşe İnci |
| author_facet | Fatma Zeynep Arslan Mehmet Karagülle Abdullah Soydan Mahmutoğlu Mehmet Semih Çakır Ayşe İnci |
| author_sort | Fatma Zeynep Arslan |
| collection | DOAJ |
| description | Aim: We examined the relationship between shear wave elastography (SWE) values and histopathological results in our study. Thus, we found the sensitivity of SWE in demonstrating early fibrosis.
Materials and Methods: A total of consecutive 70 patients with chronic hepatitis B were prospectively evaluated. The patients included in fibrosis stages (F) 0, 1, 2, 3 and 4 according to Ishak scoring were examined with SWE. SWE measurements of F2, F3 and F4 patients who were found to have early stage fibrosis were compared with those of F0 and F1 patients.
Results: The velocity+SD, and kPa+SD values in the group requiring treatment (F2, F3 and F4) were significantly higher than the group not requiring treatment (F0 and F1 )(p < 0.05). The sensitivity rate of the 1.85 cut-off value for velocity+SD was 53.8%, the positive prediction rate was 80.8%, the specificity rate was 83.3%, and the negative prediction rate was 58.1%. For kPa+SD, the cut-off value of 10.8 had a sensitivity rate of 51.3%, a positive prediction rate of 95.2%, a specificity of 96.7%, and a negative predictive rate of 60.4%. A significant correlation was observed between the fibrosis score and the kPa+SD distribution.
Conclusion: SWE can differentiate the patients requiring treatment (F2, F3 and F4) from the patients not requiring treatment. |
| format | Article |
| id | doaj-art-6c7c368bd93f4ec582f481518bde5ec2 |
| institution | Kabale University |
| issn | 2602-3741 |
| language | English |
| publishDate | 2024-02-01 |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Genel Tıp Dergisi |
| spelling | doaj-art-6c7c368bd93f4ec582f481518bde5ec22025-01-03T01:13:47ZengSelcuk University PressGenel Tıp Dergisi2602-37412024-02-01341657010.54005/geneltip.1346937154The Role of Shear Wave Elastography in Predicting Early Stage Liver FibrosisFatma Zeynep Arslan0Mehmet Karagülle1Abdullah Soydan Mahmutoğlu2Mehmet Semih Çakır3Ayşe İnci4SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL BAŞAKŞEHİR ÇAM VE SAKURA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL BAŞAKŞEHİR ÇAM VE SAKURA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜIstanbul education and Research HospitalISTANBUL UNIVERSITY, İSTANBUL FACULTY OF MEDICINE, İSTANBUL MEDICINE PR.Istanbul education and research hospitalAim: We examined the relationship between shear wave elastography (SWE) values and histopathological results in our study. Thus, we found the sensitivity of SWE in demonstrating early fibrosis. Materials and Methods: A total of consecutive 70 patients with chronic hepatitis B were prospectively evaluated. The patients included in fibrosis stages (F) 0, 1, 2, 3 and 4 according to Ishak scoring were examined with SWE. SWE measurements of F2, F3 and F4 patients who were found to have early stage fibrosis were compared with those of F0 and F1 patients. Results: The velocity+SD, and kPa+SD values in the group requiring treatment (F2, F3 and F4) were significantly higher than the group not requiring treatment (F0 and F1 )(p < 0.05). The sensitivity rate of the 1.85 cut-off value for velocity+SD was 53.8%, the positive prediction rate was 80.8%, the specificity rate was 83.3%, and the negative prediction rate was 58.1%. For kPa+SD, the cut-off value of 10.8 had a sensitivity rate of 51.3%, a positive prediction rate of 95.2%, a specificity of 96.7%, and a negative predictive rate of 60.4%. A significant correlation was observed between the fibrosis score and the kPa+SD distribution. Conclusion: SWE can differentiate the patients requiring treatment (F2, F3 and F4) from the patients not requiring treatment.https://dergipark.org.tr/tr/download/article-file/3349189shear wave elastografikaraciğerfibrozissher wave elastgraphyliverfibrosis |
| spellingShingle | Fatma Zeynep Arslan Mehmet Karagülle Abdullah Soydan Mahmutoğlu Mehmet Semih Çakır Ayşe İnci The Role of Shear Wave Elastography in Predicting Early Stage Liver Fibrosis Genel Tıp Dergisi shear wave elastografi karaciğer fibrozis sher wave elastgraphy liver fibrosis |
| title | The Role of Shear Wave Elastography in Predicting Early Stage Liver Fibrosis |
| title_full | The Role of Shear Wave Elastography in Predicting Early Stage Liver Fibrosis |
| title_fullStr | The Role of Shear Wave Elastography in Predicting Early Stage Liver Fibrosis |
| title_full_unstemmed | The Role of Shear Wave Elastography in Predicting Early Stage Liver Fibrosis |
| title_short | The Role of Shear Wave Elastography in Predicting Early Stage Liver Fibrosis |
| title_sort | role of shear wave elastography in predicting early stage liver fibrosis |
| topic | shear wave elastografi karaciğer fibrozis sher wave elastgraphy liver fibrosis |
| url | https://dergipark.org.tr/tr/download/article-file/3349189 |
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