Intestinal Biomarkers and Their Importance in Canine Enteropathies

Enteropathies are prevalent in dog internal medicine, and their diagnosis involves a lengthy process. One of the tests requested is for biomarkers, which are important as they can provide data on intestinal functionality, intensity of inflammation, and response to treatment, and can help determine t...

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Main Authors: Iago Martins Oliveira, Rafaela Rodrigues Ribeiro, Maria Eduarda Cardoso Cysneiros, Larissa Barbosa Torres, Vanessa Rezende Moraes, Lucas Rodrigues Ferreira, Wanessa Patrícia Rodrigues da Silva, Murilo Rodrigues de Souza, Rafael Antônio Lopes Xavier, Paulo Renato dos Santos Costa, Danieli Brolo Martins, Naida Cristina Borges
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Veterinary Medicine International
Online Access:http://dx.doi.org/10.1155/vmi/7409482
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author Iago Martins Oliveira
Rafaela Rodrigues Ribeiro
Maria Eduarda Cardoso Cysneiros
Larissa Barbosa Torres
Vanessa Rezende Moraes
Lucas Rodrigues Ferreira
Wanessa Patrícia Rodrigues da Silva
Murilo Rodrigues de Souza
Rafael Antônio Lopes Xavier
Paulo Renato dos Santos Costa
Danieli Brolo Martins
Naida Cristina Borges
author_facet Iago Martins Oliveira
Rafaela Rodrigues Ribeiro
Maria Eduarda Cardoso Cysneiros
Larissa Barbosa Torres
Vanessa Rezende Moraes
Lucas Rodrigues Ferreira
Wanessa Patrícia Rodrigues da Silva
Murilo Rodrigues de Souza
Rafael Antônio Lopes Xavier
Paulo Renato dos Santos Costa
Danieli Brolo Martins
Naida Cristina Borges
author_sort Iago Martins Oliveira
collection DOAJ
description Enteropathies are prevalent in dog internal medicine, and their diagnosis involves a lengthy process. One of the tests requested is for biomarkers, which are important as they can provide data on intestinal functionality, intensity of inflammation, and response to treatment, and can help determine the prognosis. This study aimed to conduct a literature review on the main serum and fecal intestinal biomarkers in dogs and proposed to refine the correlations between these indicators and enteropathies. It was observed that the main biomarkers used in the intestinal evaluation of dogs were alpha 1-proteinase inhibitory factor, immunoglobulin A, methylmalonic acid, serum folate, serum cobalamin, C-reactive protein, fecal and serum calprotectin, and dysbiosis index. However, we suggest that more research be carried out to clarify the relationship between enteropathies and intestinal biomarkers. We noticed a lack of studies on specific intestinal markers and indicator variables in healthy dogs and those with various enteropathies; moreover, no data are available on the association of these laboratory parameters.
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series Veterinary Medicine International
spelling doaj-art-6c543f156b424944808f2411dc75c8fe2024-11-21T00:00:04ZengWileyVeterinary Medicine International2042-00482024-01-01202410.1155/vmi/7409482Intestinal Biomarkers and Their Importance in Canine EnteropathiesIago Martins Oliveira0Rafaela Rodrigues Ribeiro1Maria Eduarda Cardoso Cysneiros2Larissa Barbosa Torres3Vanessa Rezende Moraes4Lucas Rodrigues Ferreira5Wanessa Patrícia Rodrigues da Silva6Murilo Rodrigues de Souza7Rafael Antônio Lopes Xavier8Paulo Renato dos Santos Costa9Danieli Brolo Martins10Naida Cristina Borges11Department of Veterinary MedicineSchool of Medical and Life SciencesSchool of Medical and Life SciencesSchool of Medical and Life SciencesDepartment of Veterinary MedicineDepartment of Veterinary MedicineDepartment of Veterinary MedicineDepartment of Veterinary MedicineDepartment of Veterinary MedicineVeterinary DepartmentDepartment of Veterinary MedicineDepartment of Veterinary MedicineEnteropathies are prevalent in dog internal medicine, and their diagnosis involves a lengthy process. One of the tests requested is for biomarkers, which are important as they can provide data on intestinal functionality, intensity of inflammation, and response to treatment, and can help determine the prognosis. This study aimed to conduct a literature review on the main serum and fecal intestinal biomarkers in dogs and proposed to refine the correlations between these indicators and enteropathies. It was observed that the main biomarkers used in the intestinal evaluation of dogs were alpha 1-proteinase inhibitory factor, immunoglobulin A, methylmalonic acid, serum folate, serum cobalamin, C-reactive protein, fecal and serum calprotectin, and dysbiosis index. However, we suggest that more research be carried out to clarify the relationship between enteropathies and intestinal biomarkers. We noticed a lack of studies on specific intestinal markers and indicator variables in healthy dogs and those with various enteropathies; moreover, no data are available on the association of these laboratory parameters.http://dx.doi.org/10.1155/vmi/7409482
spellingShingle Iago Martins Oliveira
Rafaela Rodrigues Ribeiro
Maria Eduarda Cardoso Cysneiros
Larissa Barbosa Torres
Vanessa Rezende Moraes
Lucas Rodrigues Ferreira
Wanessa Patrícia Rodrigues da Silva
Murilo Rodrigues de Souza
Rafael Antônio Lopes Xavier
Paulo Renato dos Santos Costa
Danieli Brolo Martins
Naida Cristina Borges
Intestinal Biomarkers and Their Importance in Canine Enteropathies
Veterinary Medicine International
title Intestinal Biomarkers and Their Importance in Canine Enteropathies
title_full Intestinal Biomarkers and Their Importance in Canine Enteropathies
title_fullStr Intestinal Biomarkers and Their Importance in Canine Enteropathies
title_full_unstemmed Intestinal Biomarkers and Their Importance in Canine Enteropathies
title_short Intestinal Biomarkers and Their Importance in Canine Enteropathies
title_sort intestinal biomarkers and their importance in canine enteropathies
url http://dx.doi.org/10.1155/vmi/7409482
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