Pregnancy complicated by fetal goiter following lung transplantation for idiopathic pulmonary arterial hypertension: A case study

Objective: We report a case of pregnancy following lung transplantation (LT) for idiopathic pulmonary arterial hypertension (IPAH) in Japan. Case Report: A female developed IPAH at 14 years of age and underwent a successful bilateral living-donor lobar LT from her parents at 19 years of age (gravida...

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Main Authors: Asuka Hamuro, Yoshifumi Kasuga, Saki Saito, Hiroshi Uchida, Takahiro Hiraide, Yohei Yamada, Takeshi Arimitsu, Hiroshi Date, Hiroyuki Fukushima, Mamoru Tanaka
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Taiwanese Journal of Obstetrics & Gynecology
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Online Access:http://www.sciencedirect.com/science/article/pii/S1028455924002894
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author Asuka Hamuro
Yoshifumi Kasuga
Saki Saito
Hiroshi Uchida
Takahiro Hiraide
Yohei Yamada
Takeshi Arimitsu
Hiroshi Date
Hiroyuki Fukushima
Mamoru Tanaka
author_facet Asuka Hamuro
Yoshifumi Kasuga
Saki Saito
Hiroshi Uchida
Takahiro Hiraide
Yohei Yamada
Takeshi Arimitsu
Hiroshi Date
Hiroyuki Fukushima
Mamoru Tanaka
author_sort Asuka Hamuro
collection DOAJ
description Objective: We report a case of pregnancy following lung transplantation (LT) for idiopathic pulmonary arterial hypertension (IPAH) in Japan. Case Report: A female developed IPAH at 14 years of age and underwent a successful bilateral living-donor lobar LT from her parents at 19 years of age (gravida 2, para 0). At the age of 40 years, the patient became pregnant via artificial insemination. At 28 weeks of gestation, polyhydramnios and a fetal goiter were detected on transabdominal ultrasound. The patient was diagnosed with deep vein thrombosis and pulmonary embolism. The patient underwent emergency cesarean section to deliver a male neonate weighing 1340 g (−0.41SD) at 30 weeks of gestation, with an Apgar score of 5/5 (1/5 min). Conclusion: To our knowledge, this is the first reported case of a successful pregnancy following LT in Japan. Specialists should work together to manage pregnancies following LT.
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institution Kabale University
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language English
publishDate 2025-01-01
publisher Elsevier
record_format Article
series Taiwanese Journal of Obstetrics & Gynecology
spelling doaj-art-6c455b0dd4564ae6b3d93489c6a98fb62025-01-09T06:12:53ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592025-01-01641131133Pregnancy complicated by fetal goiter following lung transplantation for idiopathic pulmonary arterial hypertension: A case studyAsuka Hamuro0Yoshifumi Kasuga1Saki Saito2Hiroshi Uchida3Takahiro Hiraide4Yohei Yamada5Takeshi Arimitsu6Hiroshi Date7Hiroyuki Fukushima8Mamoru Tanaka9Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo 160-8582, JapanDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo 160-8582, Japan; Corresponding author. Department of Obstetrics and Gynecology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo 160-8582, JapanDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo 160-8582, JapanDepartment of Cardiology, Keio University School of Medicine, Tokyo 160-8582, JapanDepartment of Pediatric Surgery, Keio University School of Medicine, Tokyo 160-8582, JapanDepartment of Thoracic Surgery, Kyoto University Graduate School of Medicine, Tokyo 160-8582, JapanDepartment of Thoracic Surgery, Kyoto University Graduate School of Medicine, Tokyo 160-8582, JapanDepartment of Pediatrics, Keio University School of Medicine, Tokyo 160-8582, JapanDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo 160-8582, JapanObjective: We report a case of pregnancy following lung transplantation (LT) for idiopathic pulmonary arterial hypertension (IPAH) in Japan. Case Report: A female developed IPAH at 14 years of age and underwent a successful bilateral living-donor lobar LT from her parents at 19 years of age (gravida 2, para 0). At the age of 40 years, the patient became pregnant via artificial insemination. At 28 weeks of gestation, polyhydramnios and a fetal goiter were detected on transabdominal ultrasound. The patient was diagnosed with deep vein thrombosis and pulmonary embolism. The patient underwent emergency cesarean section to deliver a male neonate weighing 1340 g (−0.41SD) at 30 weeks of gestation, with an Apgar score of 5/5 (1/5 min). Conclusion: To our knowledge, this is the first reported case of a successful pregnancy following LT in Japan. Specialists should work together to manage pregnancies following LT.http://www.sciencedirect.com/science/article/pii/S1028455924002894Deep vein thrombosisFetal goiterLung transplantationPregnancyPulmonary embolism
spellingShingle Asuka Hamuro
Yoshifumi Kasuga
Saki Saito
Hiroshi Uchida
Takahiro Hiraide
Yohei Yamada
Takeshi Arimitsu
Hiroshi Date
Hiroyuki Fukushima
Mamoru Tanaka
Pregnancy complicated by fetal goiter following lung transplantation for idiopathic pulmonary arterial hypertension: A case study
Taiwanese Journal of Obstetrics & Gynecology
Deep vein thrombosis
Fetal goiter
Lung transplantation
Pregnancy
Pulmonary embolism
title Pregnancy complicated by fetal goiter following lung transplantation for idiopathic pulmonary arterial hypertension: A case study
title_full Pregnancy complicated by fetal goiter following lung transplantation for idiopathic pulmonary arterial hypertension: A case study
title_fullStr Pregnancy complicated by fetal goiter following lung transplantation for idiopathic pulmonary arterial hypertension: A case study
title_full_unstemmed Pregnancy complicated by fetal goiter following lung transplantation for idiopathic pulmonary arterial hypertension: A case study
title_short Pregnancy complicated by fetal goiter following lung transplantation for idiopathic pulmonary arterial hypertension: A case study
title_sort pregnancy complicated by fetal goiter following lung transplantation for idiopathic pulmonary arterial hypertension a case study
topic Deep vein thrombosis
Fetal goiter
Lung transplantation
Pregnancy
Pulmonary embolism
url http://www.sciencedirect.com/science/article/pii/S1028455924002894
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